ChemicalBook > CAS DataBase List > RS 25344 hydrochloride
RS 25344 hydrochloride
- Product Name
- RS 25344 hydrochloride
- CAS No.
- 152815-28-6
- Chemical Name
- RS 25344 hydrochloride
- Synonyms
- RS 25344 HCl;RS-25344 hydrochloride, 10 mM in DMSO;1-(3-Nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione hydrochloride;memory,cognition,human,RS25344 hydrochloride,antineoplastic,RS-25344,Inhibitor,anti-inflammatory,RS 25344,inhibit,Phosphodiesterase (PDE),RS25344,RS 25344 hydrochloride,lymphocytes,cAMP
- CBNumber
- CB04806453
- Molecular Formula
- C19H14ClN5O4
- Formula Weight
- 411.8
- MOL File
- 152815-28-6.mol
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RS 25344 hydrochloride Property
- storage temp.
- Desiccate at RT
- solubility
- <20.59mg/ml in Water; <41.18mg/ml in DMSO
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
TRC
- Product number
- R701013
- Product name
- RS25344Hydrochloride
- Packaging
- 50mg
- Price
- $715
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7361
- Product name
- 1-(3-nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione hydrochloride
- Packaging
- 10mg
- Price
- $253
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7361
- Product name
- 1-(3-nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione hydrochloride
- Packaging
- 50mg
- Price
- $1073
- Updated
- 2021/12/16
CSNpharm
- Product number
- CSN23075
- Product name
- RS25344HCl
- Packaging
- 10mg
- Price
- $135
- Updated
- 2021/12/16
CSNpharm
- Product number
- CSN23075
- Product name
- RS25344HCl
- Packaging
- 25mg
- Price
- $301
- Updated
- 2021/12/16
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RS 25344 hydrochloride Chemical Properties,Usage,Production
Uses
RS 25344 Hydrochloride is a phosphdiesterase (PDE 4) inhibitor.
in vivo
RS-25344 hydrochloride (5 mg/kg; i.p.; twice daily for 72 h) results in significant increases in stomach weights in wild type C57BL/6 mice[3].
RS-25344 hydrochloride (1 mg/kg; i.p.; 30 min prior to food bolus) increases gastric retention in mice[3].
IC 50
PDE Ⅳ: 0.28 nM (IC50); PDE Ⅰ: >100 μM (IC50); PDE Ⅱ: 160 μM (IC50); PDE Ⅲ: 330 μM (IC50)
RS 25344 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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