1H-1,2,4-Triazole-3-thiol

Product Name: 1H-1,2,4-Triazole-3-thiol
CAS No.: 3179-31-5
Chemical Name: 1H-1,2,4-Triazole-3-thiol
Synonyms: 3-MERCAPTO-1,2,4-TRIAZOLE;MTZ;3H-1,2,4-Triazole-3-thione, 1,2-dihydro-;MERCAPTOTRIAZOL;1,2,4-TRIAZOLE-3-THIOL;ent61291;Mercapto-1,2,4-t;mercaptotriazole;4-Triazole-3-thiol;S-TRIAZOLE-3-THIOL
CBNumber: CB0481618
Molecular Formula: C2H3N3S
Formula Weight: 101.13
MOL File: 3179-31-5.mol

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1H-1,2,4-Triazole-3-thiol Property

Melting point:: 221-224 °C(lit.)
Boiling point:: 132.6±23.0 °C(Predicted)
Density: 1.385 (estimate)
vapor pressure: 1.707-1.71Pa at 25℃
refractive index: 1.5800 (estimate)
storage temp.: Inert atmosphere,Room Temperature
solubility: H2O: soluble50g/L
form: solid
pka: 9.24±0.20(Predicted)
color: White to Off-White
PH: 4.0 (85g/l, H2O, 20℃)
Water Solubility: Soluble in hot water.
BRN: 107731
InChIKey: AFBBKYQYNPNMAT-UHFFFAOYSA-N
LogP: -0.398 at 21℃ and pH5
CAS DataBase Reference: 3179-31-5(CAS DataBase Reference)
EPA Substance Registry System: 3-Mercapto-1,2,4-triazole (3179-31-5)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36-36/37/38
Safety Statements: 26-33-39-7/8-37/39
WGK Germany: 1
RTECS: XZ5267500
F: 10-23
Hazard Note: Irritant
TSCA: Yes
HS Code: 29339990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 104558
Product name: 1H-1,2,4-Triazole-3-thiol
Purity: 97%
Packaging: 10g
Price: $24.39
Updated: 2025/07/31

TCI Chemical

Product number: M0814
Product name: 3-Mercapto-1,2,4-triazole
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $44
Updated: 2025/07/31

TCI Chemical

Product number: M0814
Product name: 3-Mercapto-1,2,4-triazole
Purity: >98.0%(GC)(T)
Packaging: 100g
Price: $114
Updated: 2025/07/31

TCI Chemical

Product number: M0814
Product name: 3-Mercapto-1,2,4-triazole
Purity: >98.0%(GC)(T)
Packaging: 500g
Price: $342
Updated: 2025/07/31

TRC

Product number: D679075
Product name: 2,4-Dihydro-[1,2,4]triazole-3-thione
Packaging: 250mg
Price: $45
Updated: 2021/12/16

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1H-1,2,4-Triazole-3-thiol Chemical Properties,Usage,Production

Chemical Properties

WHITE TO SLIGHTLY YELLOW FINE CRYSTALLINE POWDER

Uses

1H-1,2,4-Triazole-3-thiol was used in a study to design a surface enhanced Raman scattering based probe for fast and accurate detection of DNA markers.

General Description

1H-1,2,4-Triazole-3-thiol is a mercapto-substituted 1,2,4-triazole ligand and exhibits tautomerism in solution. 1H-1,2,4-Triazole-3-thiol forms novel luminescent polymers with cadmium(II) salts. 1H-1,2,4-Triazole-3-thiol undergoes regioselective S-alkylation to form a series of S-substituted derivatives.

Synthesis

64-18-6

79-19-6

3179-31-5

1. In a 100 mL reaction flask, formic acid (24.2 g, 0.52 mol), water (25 mL) and aminothiourea (20 g, 0.22 mol) were added sequentially. The mixture was heated to 105 °C and the reaction was maintained for 30 min. 2. Upon completion of the reaction, the reaction solution was slowly cooled to room temperature and subsequently placed at -10°C for slow crystallization. 3. Upon completion of crystallization, the solid product was collected by filtration and dried to afford aldimine thiourea (22.3 g white solid, 85% yield). 4. To a 250 mL single-necked flask was added aldimine thiourea (12 g, 0.1 mol), water (130 mL) and sodium carbonate (21.2 g, 0.25 mol). The mixture was heated to 100 °C and the reaction was kept for 4 hours. 5. At the end of the reaction, the reaction solution was slowly cooled to room temperature and the pH was adjusted to 4-5 with dilute hydrochloric acid. 6. The reaction solution was placed at -10°C with slow stirring to induce slow precipitation of the product. 7. 7. The solid product was collected by filtration and dried to give 3-mercapto-1,2,4-triazole (5.6 g white solid, 55% yield).

References

[1] Patent: CN108689951, 2018, A. Location in patent: Paragraph 0355; 0356; 0357; 0358

1H-1,2,4-Triazole-3-thiol Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-1,2,4-Triazole-3-thiol Suppliers

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View Lastest Price from 1H-1,2,4-Triazole-3-thiol manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 1H-1,2,4-Triazole-3-thiol 3179-31-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kgs
Release date: 2025-11-18

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 1H-1,2,4-Triazole-3-thiol 3179-31-5
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%min
Supply Ability: 1000kgs
Release date: 2021-08-26

Hebei Chuanghai Biotechnology Co., Ltd

Product: 1H-1,2,4-Triazole-3-thiol 3179-31-5
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-21

3179-31-5, 1H-1,2,4-Triazole-3-thiolRelated Search:

1,2,4-Triazole 5-Methyl-1H-benzotriazole Ribavirin 1H-Benzotriazole 1-CHLOROMETHYL-1H-1,2,4-TRIAZOLE Sodium 3-mercaptopropanesulphonate Malathion 2-(METHYLTHIO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-AMINE 4-Methyl-1,2,4-triazole-3-thiol 3-Amino-5-mercapto-1,2,4-triazole ETHYL 7-AMINO-2-(METHYLTHIO)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE 3-AMINO-5-METHYLTHIO-1H-1,2,4-TRIAZOLE 4-Amino-3-hydrazino-1,2,4-triazol-5-thiol 5-PHENYL-4H-1,2,4-TRIAZOLE-3-THIOL 3-AMINO-1-METHYL-5-METHYLTHIO-1,2,4-TRIAZOLE Sodium 1,2,3-triazole-5-thiolate 7-AMINO-2-(METHYLSULFANYL)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLIC ACID 1,2,4-TRIAZOLE

1H-1,2,4-triazole-5-sulfonyl chloride

1H-1,2,4-Triazole-3-thiol intermediate

3-THIOL-1H-1,2,4-TRIAZOLE

4-triazole,3-mercapto-1h-2

4-triazole-3-thione,1,2-dihydro-3h-2

1,3,4-Triazole-2-thiol

2-Mercapto-1,3,5-triazole

5-Mercapto-1,3,4-triazole

1H-1,2,4-Triazole-3(2H)-thione

5-Mercapto-1H-1,2,4-triazole

1H-1,2,4-Triazole-3-thiol,97%

3-Mercapto-1,2,4-tri

2,3-dihydro-1H-1,2,4-triazole-3-thione

Mercapto-1,2,4-Triazol

4-Triazole-3-thiol

1H-1,2,4-Triazole-3-thiol 1,2,4-Triazole-3(5)-thiol

1H-1,2,4-Triazole-3-thiol 97%

3-Mercapto-1,2,4-trizole

3 - Mercapto - 1, 4-trichlorobenzene three azole nitrogen

Mercapto-1,2,4-t

H-1,2,4-Triazole-3-thiol

mercaptotriazole

1,2,4-TRIAZOLE-5-THIOL

1,2,4-Triazol-3-thiol

1,2,4-SODIUM TRIAZOLE

MERCAPTOTRIAZOL

1H-1,2,4-Triazole-3-thiol, 97% 10GR

3-MERCAPTO-1,2,4-TRIAZOLE FOR SYNTHESIS

3-Mercapto-1H-1,2,4-triazole, 1H-1,2,4-Triazole-3-thiol, 3-Sulphanyl-1H-1,2,4-triazole

3-Thio-1H-1,2,4-triazole

-1,2,4- three3-Mercaptotriazole

3-Mercapto-1,2,4-triazole, 97.0%(GC&T

3-Mercapto-1,2,4-triazoL

ent61291

1,2,4-triazole-3(5)-thiol

1,2,4-TRIAZOLE-3-THIOL

1H-1,2,4-TRIAZOLE-3-MERCAPTAN

1H-1,2,4-TRIAZOLE-3-THIOL

1H-1,2,4-TRIAZOLO-3-MERCAPTAN

1H-1,2,4-TRIAZOL-3-YL HYDROSULFIDE

1H-1,2,4-TRIAZOL-3-THIOL

3-MERCAPTO-1H-1,2,4-TRIAZOLE

3-MERCAPTANO-1,2,4-TRIAZOLE

3-MERCAPTO-1,2,4-TRIAZOLE

3-mercapto-1,2,4-triazole*photographic grade

1,2,4,1H-Triazole-3-thiol

3-MERCAPTO-1,2,4-TRIAZOLE 98+%

3H-1,2,4-Triazole-3-thione, 1,2-dihydro-

TIMTEC-BB SBB004364

S-TRIAZOLE-3-THIOL

MTZ

1,2,4-triazol-thiol-(3)

1,2-dihydro-3h-1,2,4-triazole-3-thione

2,4-Triazole-3-thione,1,2-dihydro-3H-1

3-Mercapto-1,2,4-triazole&gt

2,4-Dihydro-[1,2,4]triazole-3-thione

1H-1,2,4-Triazole-3-thiol 3179-31-5

3-Thiol-1H-1,2,4-thiazole