ChemicalBook > CAS DataBase List > Protac linker 5

Protac linker 5

Product Name: Protac linker 5
CAS No.: 2245697-83-8
Chemical Name: Protac linker 5
Synonyms: Protac linker 5;(S,R,S)-AHPC-C3-NH2;VH032-C4-NH2 hydrochloride;VHL Ligand-Linker Conjugates 13;E3 ligase Ligand-Linker Conjugates 28;inhibit,E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCC4NH2 hydrochloride,Inhibitor,(S,R,S) AHPC C4 NH2 hydrochloride
CBNumber: CB04845049
Molecular Formula: C27H40ClN5O4S
Formula Weight: 566.16
MOL File: 2245697-83-8.mol

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Protac linker 5 Property

form: Solid
color: Light yellow to green yellow

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Hazard and Precautionary Statements (GHS)

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Protac linker 5 Chemical Properties,Usage,Production

Uses

(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].

IC 50

VHL

References

[1] Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9. DOI:10.1016/j.chembiol.2019.11.004

Protac linker 5 Preparation Products And Raw materials

Raw materials

Preparation Products

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2245697-83-8, Protac linker 5Related Search:

Protac linker 5

E3 ligase Ligand-Linker Conjugates 28

(S,R,S)-AHPC-C3-NH2

VH032-C4-NH2 hydrochloride

VHL Ligand-Linker Conjugates 13

inhibit,E3 Ligase Ligand-Linker Conjugates,(S,R,S)AHPCC4NH2 hydrochloride,Inhibitor,(S,R,S) AHPC C4 NH2 hydrochloride

2245697-83-8