(1r,3r)-3-(cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile

Product Name: (1r,3r)-3-(cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile
CAS No.: 2127109-84-4
Chemical Name: (1r,3r)-3-(cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile
Synonyms: Tyk2-IN-8;PF6826647;PF 6826647;PF-6826647;PF-06826647;Ropsacitinib;PF-06826647( Tyk2-IN-8);Ropsacitinib (PF-06826647;Cyclobutaneacetonitrile, 3-cyano-1-[4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]-1H-pyrazol-1-yl]-, trans-;cis-3-(Cyanomethyl)-3-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]-1H-pyrazol-1-yl}cyclobutanecarbonitrile
CBNumber: CB04923831
Molecular Formula: C20H17N9
Formula Weight: 383.41
MOL File: 2127109-84-4.mol

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(1r,3r)-3-(cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile Property

Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 16.67 mg/mL (43.48 mM)
pka: 0.98±0.19(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0101462
Product name: PF-06826647
Purity: 99.82%
Packaging: 5mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0101462
Product name: PF-06826647
Purity: 99.82%
Packaging: 10mg
Price: $990
Updated: 2021/12/16

ChemScene

Product number: CS-0101462
Product name: PF-06826647
Purity: 99.82%
Packaging: 50mg
Price: $2550
Updated: 2021/12/16

Crysdot

Product number: CD31005026
Product name: PF-06826647
Purity: 98%
Packaging: 5mg
Price: $790
Updated: 2021/12/16

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(1r,3r)-3-(cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile Chemical Properties,Usage,Production

Uses

trans-3-Cyano-1-[4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]-1H-pyrazol-1-yl]cyclobutaneacetonitrile is a selective inhibitor of Tyrosine Kinase 2 (TYK2).

(1r,3r)-3-(cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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(1r,3r)-3-(cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile Suppliers

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View Lastest Price from (1r,3r)-3-(cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile manufacturers

Jinan Million Pharmaceutical Co., Ltd

Product: Ropsacitinib/PF-06826647 2127109-84-4
Price: US $2.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1200KG/M
Release date: 2023-08-11

2127109-84-4, (1r,3r)-3-(cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrileRelated Search:

(1r,3r)-3-(cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile

PF-06826647

Tyk2-IN-8

Cyclobutaneacetonitrile, 3-cyano-1-[4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]-1H-pyrazol-1-yl]-, trans-

PF-06826647( Tyk2-IN-8)

Ropsacitinib (PF-06826647

trans-3-(Cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile

Ropsacitinib

cis-3-(Cyanomethyl)-3-{4-[6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]-1H-pyrazol-1-yl}cyclobutanecarbonitrile

PF 6826647

PF6826647

PF-6826647

2127109-84-4