ETILEFRINE-D5

Product Name: ETILEFRINE-D5
CAS No.: 709-55-7
Chemical Name: ETILEFRINE-D5
Synonyms: S 40032;Etilefrin;S 40032-7;Aids001656;Etilephrine;Aids-001656;dl-Etilefrin;Etiladrianol;Etilefrin-d5;ETILEFRINE-D5
CBNumber: CB0495639
Molecular Formula: C10H15NO2
Formula Weight: 181.23
MOL File: 709-55-7.mol

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ETILEFRINE-D5 Property

Melting point:: 147-148°
Boiling point:: 314.35°C (rough estimate)
Density: 1.0918 (rough estimate)
refractive index: 1.5464 (estimate)
pka: 9.81±0.10(Predicted)
LogP: 3.2 at 25℃ and pH5.5

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0008685
Product name: ETILEFRINE
Purity: 95.00%
Packaging: 1G
Price: $136.5
Updated: 2021/12/16

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ETILEFRINE-D5 Chemical Properties,Usage,Production

Originator

Circupon,Troponwerke,W. Germany

Uses

Etilefrin is a sympathomimetic drug that increases the pulse rate, cardiac output, stroke volume, central venous pressure and mean arterial pressure of healthy individuals. Etilefrin has both beta 1 and alpha adrenergic effects on humans and is mainly used for the treatment of patients with orthostatic hypotension.

Uses

ETILEFRINE-D5 is a sympathomimetic drug that increases the pulse rate, cardiac output, stroke volume, central venous pressure and mean arterial pressure of healthy individuals. Etilefrin has both beta 1 and alpha adrenergic effects on humans and is mainly used for the treatment of patients with orthostatic hypotension.

Definition

ChEBI: 3-[2-(ethylamino)-1-hydroxyethyl]phenol is a member of phenols.

Manufacturing Process

30 parts of 1-(3'-hydroxyphenyl)-2-(N-benzylaminomethyl)-ethan-1-one are mixed with 100 parts of pyridine and 30 parts of pivalic anhydride and dissolved while warming. After heating for 1 hour under reflux, the acylation is complete. After concentrating the reaction solution, the product is precipitated from acetone/ether. Yield: 96.4% of 1-(3'-pivaloyloxyphenyl)-2- (N-benzylaminomethyl)-ethan-1-one.
3 parts of palladium/charcoal (10% strength) are prehydrogenated in water, thereafter 10 parts of 1-(3'-pivaloyloxyphenyl)-2-(N-benzylaminoethyl)-ethan- 1-one, dissolved in a 10-fold amount of water, are added dropwise at room temperature and hydrogenation is carried out until 1 mol of hydrogen has been taken up. After filtering off the catalyst, a further 3 parts of palladium/charcoal are added and hydrogenation is carried out until a further mol of hydrogen has been taken up. The catalyst is separated off and after removal of the solvent the hydrogenation product is reprecipitated from acetone/petroleum ether and from methanol/ether until it is pure according to thin layer chromatography. Yield: 38.8% of 1-(3'-pivaloyloxyphenyl)-2- ethylaminoethanol-1 hydroxide, melting point 208°C to 209°C.

Therapeutic Function

Tranquilizer

ETILEFRINE-D5 Preparation Products And Raw materials

Raw materials

Preparation Products

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ETILEFRINE-D5 Suppliers

China 7 India 4 United States 1 Global 12

Shanghai TaoSu Biochemical Technology Co., Ltd.

Tel: 021-33632979
Fax: 021-34692979
Email: info@tsbiochem.com
Country: China
ProdList: 8065
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 56902
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15357
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Beijing xinyanhui pharmaceutical research and development co., LTD

Tel: 13969155946
Email: 1461866103@qq.com
Country: China
ProdList: 16111
Advantage: 58

Block Chemical Technology (Shanghai) Co., Ltd.

Tel: 021-20432219 13918097649
Fax: QQ79021576
Email: li_jinfei@acblock-lab.com
Country: China
ProdList: 9962
Advantage: 58

LEAPCHEM CO., LTD.

Tel: +86-852-30606658
Email: market18@leapchem.com
Country: China
ProdList: 43340
Advantage: 58

709-55-7, ETILEFRINE-D5Related Search:

Ibrutinib Impurity 27 2-(Ethylamino)ethanol ETILEFRINE-D5

ETILEFRINE-D5

3-[2-(ethylamino)-1-hydroxyethyl]phenol

Etilefrinhydrochlorid

(+-)-Etilefrin

1-(3-Hydroxyphenyl)-2-(ethylamino)ethanol

Benzenemethanol, α-[(ethylamino)methyl]-3-hydroxy-

Benzyl alcohol, α-[(ethylamino)methyl]-m-hydroxy- (6CI, 8CI)

dl-Etilefrin

Ethylphenylephrine

Etiladrianol

Etilefrin

m-Hydroxy-α-(ethylaminomethyl)benzyl alcohol

N-Ethylnorphenylephrine

Racemic etilefrine

S 40032

S 40032-7

α-(m-Hydroxyphenyl)-β-(ethylamino)ethanol

α-[(Ethylamino)methyl]-m-hydroxybenzyl alcohol

Etilephrine

m-[2-(Ethylamino)-1-hydroxyethyl]phenol

.alpha.-[(Ethylamino)methyl]-3-hydroxybenzenemethanol hydrochloride

943-17-9 (Hydrochloride)

Aids001656

Aids-001656

Benzenemethanol, .alpha-[(ethylamino)methyl]-3-hydroxy-, hydrochloride

Ethylephrine hydrochloride

Etilefrin-d5

Etilefrin DISCONTINUED, offer E932950

AMP-activated protein kinase,Beta Receptor,Inhibitor,AMPK activator,Adrenergic Receptor,Etilefrine,α adrenergic Agonist,AMPK,postural hypotension,inhibit

709-55-7

Amines, Aromatics, Drug Analogues, Pharmaceuticals, Intermediates & Fine Chemicals