BI-6C9
- Product Name
- BI-6C9
- CAS No.
- 791835-21-7
- Chemical Name
- BI-6C9
- Synonyms
- N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide;N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide;Butanamide, N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-;Inhibitor,fission,Neurodegeneration,Bid,BI6C9,BI 6C9,Mitochodondrial,death,Mitochondria,Apoptosis,inhibit,Glutamate,stress,Neuronal,Bcl-2,Mitochondrial,Mitochondrial Metabolism,potential,cell,Oxidative,membrane,BI-6C9,BI-6C-9
- CBNumber
- CB0496964
- Molecular Formula
- C23H25N3O4S2
- Formula Weight
- 471.59
- MOL File
- 791835-21-7.mol
BI-6C9 Property
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO: 24 mg/mL, soluble
- form
- solid
- pka
- 11.58±0.50(Predicted)
- color
- off-white
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B0186
- Product name
- BI-6C9
- Purity
- ≥97% (HPLC), solid
- Packaging
- 1mg
- Price
- $93.4
- Updated
- 2024/03/01
- Product number
- B0186
- Product name
- BI-6C9
- Purity
- ≥97% (HPLC), solid
- Packaging
- 5mg
- Price
- $324
- Updated
- 2024/03/01
- Product number
- 17265
- Product name
- BI-6C9
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $56
- Updated
- 2024/03/01
- Product number
- 17265
- Product name
- BI-6C9
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $241
- Updated
- 2024/03/01
- Product number
- 17265
- Product name
- BI-6C9
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $429
- Updated
- 2024/03/01
BI-6C9 Chemical Properties,Usage,Production
Uses
BH3-interacting domain (Bid) is cleaved by caspase-8 to produce the truncated protein tBid, which facilitates cytochrome c release from mitochondria and drives apoptosis. BI-6C9 is an inhibitor of tBid (Kd = 20 μM), blocking the release of both cytochrome c and second mitochondria-derived activator of caspase from mitochondria. It prevents apoptosis in neurons treated with glutamate or oxygen-glucose deprivation. BI-6C9 (10 μM) also inhibits the nuclear translocation of apoptosis-inducing factor AIF, preventing the death of ovarian OVCAR-3 cancer cells induced by IFN-α2a.
BI-6C9 Preparation Products And Raw materials
Raw materials
Preparation Products
BI-6C9 Suppliers
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9708
- Advantage
- 58
- Tel
- 010-60605840 18892239720
- Fax
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 12308
- Advantage
- 58
- Tel
- 400-9205774
- sales@glpbio.cn
- Country
- China
- ProdList
- 6870
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6393
- Advantage
- 58
- Tel
- 88888888888
- hongquchem@qq.com
- Country
- China
- ProdList
- 5132
- Advantage
- 58
- Tel
- 021-69568360 18916172912
- order@med-bio.cn
- Country
- China
- ProdList
- 8141
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44941
- Advantage
- 58
- Tel
- 18051384581
- sales@chemhifuture.com
- Country
- China
- ProdList
- 3059
- Advantage
- 58
- Tel
- 010-60605840
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29778
- Advantage
- 58
- Tel
- 0371-65741762
- Fax
- QQ：2860768577
- sales@hasunny.com
- Country
- China
- ProdList
- 2380
- Advantage
- 58