BI-6C9

Product Name: BI-6C9
CAS No.: 791835-21-7
Chemical Name: BI-6C9
Synonyms: N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide;N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide;Butanamide, N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-;Inhibitor,fission,Neurodegeneration,Bid,BI6C9,BI 6C9,Mitochodondrial,death,Mitochondria,Apoptosis,inhibit,Glutamate,stress,Neuronal,Bcl-2,Mitochondrial,Mitochondrial Metabolism,potential,cell,Oxidative,membrane,BI-6C9,BI-6C-9
CBNumber: CB0496964
Molecular Formula: C23H25N3O4S2
Formula Weight: 471.59
MOL File: 791835-21-7.mol

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BI-6C9 Property

Density: 1.36±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility: DMSO: 24 mg/mL, soluble
form: solid
pka: 11.58±0.50(Predicted)
color: off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B0186
Product name: BI-6C9
Purity: ≥97% (HPLC), solid
Packaging: 1mg
Price: $93.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: B0186
Product name: BI-6C9
Purity: ≥97% (HPLC), solid
Packaging: 5mg
Price: $324
Updated: 2024/03/01

Cayman Chemical

Product number: 17265
Product name: BI-6C9
Purity: ≥98%
Packaging: 1mg
Price: $56
Updated: 2024/03/01

Cayman Chemical

Product number: 17265
Product name: BI-6C9
Purity: ≥98%
Packaging: 5mg
Price: $241
Updated: 2024/03/01

Cayman Chemical

Product number: 17265
Product name: BI-6C9
Purity: ≥98%
Packaging: 10mg
Price: $429
Updated: 2024/03/01

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BI-6C9 Chemical Properties,Usage,Production

Uses

BH3-interacting domain (Bid) is cleaved by caspase-8 to produce the truncated protein tBid, which facilitates cytochrome c release from mitochondria and drives apoptosis. BI-6C9 is an inhibitor of tBid (Kd = 20 μM), blocking the release of both cytochrome c and second mitochondria-derived activator of caspase from mitochondria. It prevents apoptosis in neurons treated with glutamate or oxygen-glucose deprivation. BI-6C9 (10 μM) also inhibits the nuclear translocation of apoptosis-inducing factor AIF, preventing the death of ovarian OVCAR-3 cancer cells induced by IFN-α2a.

BI-6C9 Preparation Products And Raw materials

Raw materials

Preparation Products

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BI-6C9 Suppliers

China 14 Switzerland 1 United States 6 USA 1 Global 22

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52927
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354
Email: support@targetmol.com
Country: United States
ProdList: 19973
Advantage: 58

791835-21-7, BI-6C9Related Search:

N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide

Butanamide, N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-

N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide

Inhibitor,fission,Neurodegeneration,Bid,BI6C9,BI 6C9,Mitochodondrial,death,Mitochondria,Apoptosis,inhibit,Glutamate,stress,Neuronal,Bcl-2,Mitochondrial,Mitochondrial Metabolism,potential,cell,Oxidative,membrane,BI-6C9,BI-6C-9

791835-21-7