ChemicalBook > CAS DataBase List > 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE

Product Name
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
CAS No.
29331-92-8
Chemical Name
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE
Synonyms
GP 47779;BIA 2-005;GP 47779-d3;BIA 2-005-d3;Licarbazepine;Hydroxycarbamazepine;Licarbazepine Racemate;10,11-Dihydro-10-hydroxy;LICARBAZEPINE SEE 16178912;Oxcarbazepine Hydroxy Impurity
CBNumber
CB0500702
Molecular Formula
C15H14N2O2
Formula Weight
254.28
MOL File
29331-92-8.mol
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10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Property

Melting point:
186-189°C
Boiling point:
431.3±55.0 °C(Predicted)
Density 
1.336
Flash point:
2℃
storage temp. 
-20°C
solubility 
Soluble to 100 mM in DMSO and to 50 mM in ethanol
form 
Solid
pka
13.75±0.20(Predicted)
color 
White to off-white
BRN 
1540211
InChIKey
BMPDWHIDQYTSHX-UHFFFAOYSA-N
CAS DataBase Reference
29331-92-8
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Safety

Hazard Codes 
N,Xn,F
Risk Statements 
51/53-36-20/21/22-11
Safety Statements 
61-36/37-26-16
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3294
Product name
Licarbazepine
Purity
pharmaceutical secondary standard, certified reference material
Packaging
50MG
Price
$344
Updated
2024/03/01
Sigma-Aldrich
Product number
D-091
Product name
10,11-Dihydro-10-Hydroxycarbamazepine solution
Purity
1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$140
Updated
2024/03/01
Sigma-Aldrich
Product number
61347
Product name
10,11-Dihydro-10-hydroxycarbamazepine
Purity
analytical standard
Packaging
25mg
Price
$1000
Updated
2024/03/01
Cayman Chemical
Product number
18467
Product name
10,11-dihydro-10-hydroxy Carbamazepine
Purity
≥98%
Packaging
5mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
18467
Product name
10,11-dihydro-10-hydroxy Carbamazepine
Purity
≥98%
Packaging
10mg
Price
$94
Updated
2024/03/01
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10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A metabolite of Oxcarbazepine

Uses

A labelled metabolite of Oxcarbazepine

Uses

10,11-dihydro-10-hydroxy Carbamazepinee is the active metabolite of oxcarbazepine . Oxcarbazepine is rapidly and almost completely converted to 10,11-dihydro-10-hydroxycarbamazepine, which then demonstrates anticonvulsant efficacy by modulating several ion channels and receptors. ?10,11-dihydro-10-hydroxy Carbamazepine is reported to inhibit both voltage-gated Na+ and Ca2+ channels, to potentiate voltage-gated K+ channels, to antagonize adenosine A1 receptors, to increase dopaminergic transmission, and to inhibit glutamate release.

Definition

ChEBI: A dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel b ocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine.

storage

Store at RT

10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Preparation Products And Raw materials

Raw materials

Preparation Products

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10,11-DIHYDRO-10-HYDROXYCARBAZEPINE Suppliers

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View Lastest Price from 10,11-DIHYDRO-10-HYDROXYCARBAZEPINE manufacturers

Career Henan Chemical Co
Product
10,11-DIHYDRO-10-HYDROXYCARBAZEPINE 29331-92-8
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-01-30

29331-92-8, 10,11-DIHYDRO-10-HYDROXYCARBAZEPINERelated Search:


  • Oxcarbazepine Hydroxy Impurity
  • 5-Carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepine-10-ol
  • 6-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
  • 10,11-Dihydro-10-hydroxy-5H-dibenz(Z)[b,f]azepin-5-carboxamide
  • 10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxaMide
  • 10,11-Dihydro-10-hydroxy
  • (±)-10-Hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxaMide
  • 5H-Dibenz[b,f]azepine-5-carboxaMide,10,11-dihydro-10-hydroxy-
  • 10,11-Dihydro-10-Hydroxycarbamazepine solution
  • 5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
  • 10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
  • 10-Hydroxy-10,11-dihydrocarbamezepine
  • BIA 2-005
  • GP 47779
  • Licarbazepine
  • 10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide-d3
  • 10,11-Dihydro-10-hydroxycarbazepine-d3
  • 10-Hydroxy-10,11-dihydrocarbamezepine-d3
  • BIA 2-005-d3
  • GP 47779-d3
  • LICARBAZEPINE SEE 16178912
  • Hydroxycarbamazepine
  • 10-Hydroxy-10,11-dihydrocarbamazepi
  • Dihydrohydroxy carbamazepine-D4
  • 10,11-hydroxy-10,11 Dihydrocarbamezer
  • Licarbazepine Racemate
  • 10,11-Dihydro-10-hydroxy-Carbamazepin
  • (±)-10-Hydroxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carbox...
  • 10,11-Dihydro-10-hydroxy carbamazepine D7
  • 10,11-dihydro-10-Hydroxy CarbamazepineQ: What is 10,11-dihydro-10-Hydroxy Carbamazepine Q: What is the CAS Number of 10,11-dihydro-10-Hydroxy Carbamazepine Q: What is the storage condition of 10,11-dihydro-10-Hydroxy Carbamazepine Q: What are the applications of 10,11-dihydro-10-Hydroxy Carbamazepine
  • 1H-Benzimidazole,2-(6-methoxyethyl)-
  • (±) -10,11-Dihydro-10-hydroxy-5H-dibenzo[b,f]azepine-5-carboxamide
  • 10,11-Dihydro-10-hydroxycarbamazepine in methanol
  • Licarbazepine (10,11-Dihydro-10-hydroxycarbamazepine), Active oxcarbazepine metabolite
  • 29331-92-8
  • 84006-10-4
  • C15H11D3N2O2
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Isotope Labeled Compounds