DOCUSATE CALCIUM (500 MG) Property

Boiling point:

339℃[at 101 325 Pa]

Density 

1.021[at 20℃]

vapor pressure 

0Pa at 20℃

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly, Heated), Methanol (Slightly)

form 

Solid

color 

White to Off-White

Water Solubility 

6g/L at 20℃

Stability:

Hygroscopic

LogP

8.9 at 20℃

Safety

HS Code 

2917197055

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

DOCUSATE CALCIUM (500 MG) Chemical Properties,Usage,Production

Originator

Surfak,Hoechst,US,1959

Uses

Stool softener.

Uses

Calcium salt of Docusate, used for the treatment of constipation, acting as a laxative or stool softener.

Manufacturing Process

88 g of dioctyl sodium sulfosuccinate is first dissolved in 100 cc of isopropanol and 25 g of calcium chloride is dissolved in 50 cc of methanol. The solutions are then mixed and stirred for about 3 hours and then cooled with ice. The sodium chloride which precipitates in the cool mixture is removed by filtration and most of the alcohol is evaporated from the resulting filtrate with heat. The liquid remaining is poured into 88 cc of water, and the resulting precipitate washed with water until free of chloride ion. The washed calcium salt is then dried.

brand name

Surfak (Hoechst-Roussel).

Therapeutic Function

Stool softener

Flammability and Explosibility

Non flammable