Dichloro-1,2-dithiacyclopentenone
- Product Name
- Dichloro-1,2-dithiacyclopentenone
- CAS No.
- 1192-52-5
- Chemical Name
- Dichloro-1,2-dithiacyclopentenone
- Synonyms
- DDCP;4,5-dichlorodithiol-3-one;2,2-Diphenyl-3-butynamide;dichloro-1,2-dithiol-3-one;4,5-Dichloro-1,2-dithiol-3-one;2,3-Dichloro-1,2-dithiol-3-one;Dichloro-1,2-dihiacyclopenenone;4,5-dichloro-3-oxo-1,2-dithiole;4,5-Dichlor-3H-1,2-dithiol-3-on;4,5-dichloro-3h-2-dithiole-3-one
- CBNumber
- CB0502579
- Molecular Formula
- C3Cl2OS2
- Formula Weight
- 187.07
- MOL File
- 1192-52-5.mol
Dichloro-1,2-dithiacyclopentenone Property
- Melting point:
- 52-56 °C
- Flash point:
- 200 °C
- storage temp.
- 2-8°C
- form
- Solid
- BRN
- 1342220
- InChI
- InChI=1S/C3Cl2OS2/c4-1-2(5)7-8-3(1)6
- InChIKey
- QGSRKGWCQSATCL-UHFFFAOYSA-N
- SMILES
- S1C(Cl)=C(Cl)C(=O)S1
- EPA Substance Registry System
- 4,5-Dichloro-1,2-dithiacyclopentenone (1192-52-5)
Safety
- Hazard Codes
- T
- Risk Statements
- 25-37/38
- Safety Statements
- 36/37/39-45
- RIDADR
- 2811
- WGK Germany
- 3
- RTECS
- JP1290000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Toxicity
- mouse,LD50,intravenous,13mg/kg (13mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#07423,
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H335May cause respiratory irritation
H400Very toxic to aquatic life
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P273Avoid release to the environment.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- HCH0036481
- Product name
- DICHLORO-1,2-DITHIACYCLOPENTENONE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $1289.76
- Updated
- 2021/12/16
- Product number
- CD11334903
- Product name
- 4,5-Dichloro-3H-1,2-dithiol-3-one
- Purity
- 97%
- Packaging
- 10g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- CD11334903
- Product name
- 4,5-Dichloro-3H-1,2-dithiol-3-one
- Purity
- 97%
- Packaging
- 25g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- CM202713
- Product name
- 4,5-Dichloro-3H-1,2-dithiol-3-one
- Purity
- 97%
- Packaging
- 100g
- Price
- $234
- Updated
- 2021/12/16
- Product number
- CD11334903
- Product name
- 4,5-Dichloro-3H-1,2-dithiol-3-one
- Purity
- 97%
- Packaging
- 100g
- Price
- $250
- Updated
- 2021/12/16
Dichloro-1,2-dithiacyclopentenone Chemical Properties,Usage,Production
Uses
4,5-Dichloro-3H-1,2-dithiol-3-one (Dichloro-1,2-dithiacyclopentenone) is an E. coli FabH inhibitor (IC50: 2.9 μM). 4,5-Dichloro-3H-1,2-dithiol-3-one can be used as a slimicide in the manufacture of food-contact paper and paperboard [1][2].
Synthesis
Using tetrachloroethylene and trichloromethane as the starting materials, 4,5-dichloro-1,2-dithiolenone was obtained by Foucault reaction, alkaline dechlorination to alkene, and catalytic and sulfur cyclization.
Purification Methods
Dissolve it in CH2Cl2 (1g in 250ml), filter, wash it twice with H2O, evaporate and distil the residue in vacuo and then recrystallise it from pet ether. IR: max 1650 cm-1. [Boberg Justus Liebigs Ann Chem 679 109 1964, Boberg Justus Liebigs Ann Chem 693 212 1966, Beilstein 19/4 V 72.]
References
[1] Song X, et al. Synthesis and antibacterial activity of cinnamaldehyde acylhydrazone with a 1,4-benzodioxan fragment as a novel class of potent β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitor. Chem Pharm Bull (Tokyo). 2014;62(11):1110-8. DOI:10.1248/cpb.c14-00485
[2] Mary S. Wolfe, et al. Chapter. National Toxicology Program. Book. Toxicology and Regulatory Process. 2006. Pages. 32
Dichloro-1,2-dithiacyclopentenone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Dichloro-1,2-dithiacyclopentenone manufacturers
- Product
- Dichloro-1,2-dithiacyclopentenone in stock Factory 1192-52-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- TOP 3 Factory in China
- Supply Ability
- Top 3 largest production capacity Factory
- Release date
- 2019-04-03
- Product
- Dichloro-1,2-dithiacyclopentenone 1192-52-5
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 784
- Release date
- 2019-09-02