ChemicalBook > CAS DataBase List > PKI 166 hydrochloride

PKI 166 hydrochloride

Product Name
PKI 166 hydrochloride
CAS No.
2230253-82-2
Chemical Name
PKI 166 hydrochloride
Synonyms
PKI 166 hydrochloride;PKI 166 hydrochloride,PKI166 hydrochloride;(R)-4-(4-((1-Phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrochloride , PKI-166 hydrochloride
CBNumber
CB05185856
Molecular Formula
C20H19ClN4O
Formula Weight
366.85
MOL File
2230253-82-2.mol
More
Less

PKI 166 hydrochloride Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Tocris
Product number
4941
Product name
PKI166hydrochloride
Purity
≥98%(HPLC)
Packaging
10
Price
$185
Updated
2021/12/16
Usbiological
Product number
256278
Product name
PKI 166 hydrochloride
Packaging
10mg
Price
$475
Updated
2021/12/16
More
Less

PKI 166 hydrochloride Chemical Properties,Usage,Production

Biological Activity

PKI-166 hydrochloride is a potent, selective, and orally bioactive EGFR tyrosine kinase inhibitor with IC50 of 0.7 nM.

in vivo

PKI-166 hydrochloride (100 mg/kg; po; daily; for 29 days) inhibits of pancreatic cancer growth.

Animal Model: < /td> Male athymic nude mice with L3.6pl cells xenograft (8-12 weeks)
Dosage: < /td> 100 mg/kg
Administration: Oral administration; daily; for 29 days
Result: Significantly decreased median tumor volume.

target

IC50: 0.7 nM (EGFR tyrosine kinase)

storage

Store at +4°C

PKI 166 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

PKI 166 hydrochloride Suppliers

China 8 United States 5 Global 13
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

2230253-82-2, PKI 166 hydrochlorideRelated Search:


  • PKI 166 hydrochloride
  • PKI 166 hydrochloride,PKI166 hydrochloride
  • (R)-4-(4-((1-Phenylethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrochloride , PKI-166 hydrochloride
  • 2230253-82-2