ChemicalBook > CAS DataBase List > 4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)-

4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)-

Product Name
4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)-
CAS No.
1380089-81-5
Chemical Name
4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)-
Synonyms
CPI-0610 carboxylic acid;CPI 0610 carboxylic acid,CPI0610 carboxylic acid;4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)-;(S)-2-(6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetic acid
CBNumber
CB05481860
Molecular Formula
C20H15ClN2O3
Formula Weight
366.8
MOL File
1380089-81-5.mol
More
Less

4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)- Property

Boiling point:
593.5±50.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
pka
4.19±0.10(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)- Chemical Properties,Usage,Production

Uses

CPI-0610 carboxylic acid is a ligand for target protein for PROTACT. CPI-0610 carboxylic acid is a potent bromodomain and extra-terminal (BET) protein inhibitor. CPI-0610 carboxylic acid has the potential in the therapy of multiple myeloma[1].

References

[1] Albrecht BK, et al. Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials. J Med Chem. 2016 Feb 25;59(4):1330-9. DOI:10.1021/acs.jmedchem.5b01882

4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)- Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)- Suppliers

China 11 United States 1 Global 12
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3505
Advantage
58
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7777
Advantage
56
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32467
Advantage
58
Birdo (Shanghai) Medical Technology Co., Ltd.
Tel
021-58099077-8041 18601625411
Email
sales@birdotech.com
Country
China
ProdList
9993
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11972
Advantage
58
Nantong Hanfang Biotechnology Co. , Ltd.
Tel
hanfangpharma@126.com; 18616537568
Email
hanfangpharma@126.com
Country
China
ProdList
25801
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6813
Advantage
58
Adooq Bioscience LLC
Tel
400-025-6535
Email
sales@adooq.cn
Country
China
ProdList
6215
Advantage
58
Shanghai Amole Biotechnology Co., Ltd.
Tel
18916360931 18916360931
Email
2596183085@qq.com
Country
China
ProdList
17238
Advantage
58

1380089-81-5, 4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)-Related Search:


  • 4H-Isoxazolo[5,4-d][2]benzazepine-4-acetic acid, 6-(4-chlorophenyl)-1-methyl-, (4S)-
  • CPI-0610 carboxylic acid
  • CPI 0610 carboxylic acid,CPI0610 carboxylic acid
  • (S)-2-(6-(4-chlorophenyl)-1-methyl-4H-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetic acid
  • 1380089-81-5