ChemicalBook > CAS DataBase List > 2’-Chloro-N6-(3-methoxy)benzyl adenosine
2’-Chloro-N6-(3-methoxy)benzyl adenosine
- Product Name
- 2’-Chloro-N6-(3-methoxy)benzyl adenosine
- CAS No.
- 722504-73-6
- Chemical Name
- 2’-Chloro-N6-(3-methoxy)benzyl adenosine
- Synonyms
- 2’-Chloro-N6-(3-methoxy)benzyladenosine;2’-Chloro-N6-(3-methoxy)benzyl adenosine;Adenosine, 2-chloro-N-[(3-methoxyphenyl)methyl]- (9CI);(2R,3R,4S,5R)-2-(2-chloro-6-((3-methoxybenzyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
- CBNumber
- CB05493049
- Molecular Formula
- C18H20ClN5O5
- Formula Weight
- 421.83
- MOL File
- 722504-73-6.mol
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2’-Chloro-N6-(3-methoxy)benzyl adenosine Property
- Boiling point:
- 661.9±65.0 °C(Predicted)
- Density
- 1.68±0.1 g/cm3(Predicted)
- pka
- 13.06±0.70(Predicted)
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2’-Chloro-N6-(3-methoxy)benzyl adenosine Chemical Properties,Usage,Production
Uses
2’-Chloro-N6-(3-methoxy)benzyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
2’-Chloro-N6-(3-methoxy)benzyl adenosine Preparation Products And Raw materials
Raw materials
Preparation Products
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