ChemicalBook > CAS DataBase List > Lenacapavir
Lenacapavir
- Product Name
- Lenacapavir
- CAS No.
- 2189684-44-2
- Chemical Name
- Lenacapavir
- Synonyms
- Lenacapavir;1H-Cyclopropa[3,4]cyclopenta[1,2]pyrazole-1-acetamide, N-[(1S)-1-[3-[4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylsulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)-;GS-6207;Sunitinib Impurity 72;HIV-1 capsid inhibitor GS-6207;13C,2H3]-Lenacapavir , isomeric mixture;13C,2H3]-Lenacapavir (Major),isomers mixture;MT-4,Inhibitor,antiretroviral,Lenacapavir,inhibit,GS 6207,capsid,Human immunodeficiency virus,HIV,GS6207,HIV-1,PBMCs;1H-Cyclopropa[3,4]cyclopenta[1,2-c]pyrazole, N-[(1S)-1-[3-[4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-[3-methyl-3-(methylsulfonyl)-1-butyn-1-yl]-2-pyridinyl]-2-(3,5-difluorophenyl)ethyl]-5,5-difluoro-3b,4,4a,5-tetrahydro-3-(trifluoromethyl)-, (3bS,4aR)-;N-((S)-1-(3-(4-Chloro-3-(methylsulfonamido)-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl)-6-(3-methyl-3-(methylsulfonyl)but-1-yn-1-yl)pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-((3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)acetamide
- CBNumber
- CB05544792
- Molecular Formula
- C39H32ClF10N7O5S2
- Formula Weight
- 968.28
- MOL File
- 2189684-44-2.mol
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Lenacapavir Property
- Density
- 1.62±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 250 mg/mL (258.19 mM)
- form
- Solid
- pka
- 4.63±0.30(Predicted)
- color
- White to light yellow
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0094695
- Product name
- Lenacapavir
- Purity
- 98.49%
- Packaging
- 5mg
- Price
- $950
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0094695
- Product name
- Lenacapavir
- Purity
- 98.49%
- Packaging
- 10mg
- Price
- $1600
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0094695
- Product name
- Lenacapavir
- Purity
- 98.49%
- Packaging
- 25mg
- Price
- $2800
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0094695
- Product name
- Lenacapavir
- Purity
- 98.49%
- Packaging
- 50mg
- Price
- $4200
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0094695
- Product name
- Lenacapavir
- Purity
- 98.49%
- Packaging
- 100mg
- Price
- $6900
- Updated
- 2021/12/16
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Lenacapavir Chemical Properties,Usage,Production
Description
HIV-1 capsid inhibitor GS-6207 (lenacapavir) is a drug being developed by Gilead Sciences, Inc. It is a first-in-class, oral HIV-1 capsid inhibitor.
Uses
Lenacapavir can be useful in capsid inhibition in multidrug-resistant HIV-1 infection.
Application
Lenacapasvir was first approved in the European Union in 2022 for use in combination with other antiretroviral drugs to treat multidrug-resistant adults with HIV and those who are unable to establish a suppressive antiviral regimen. Subsequently, the drug also received similar approvals in Canada and the United States. Lenacapasvir is available as an oral and injectable therapy and is a long-acting, extended-release drug for the treatment of HIV-1. When used in combination with other antiretroviral drugs, it may only need to be administered once every 6 months, aiming to improve patient compliance and medication adherence.
Mechanism of action
Lenacapasvir works by inhibiting the HIV-1 capsid protein, a protein shell that encapsulates the viral genetic material and is involved in multiple stages of the HIV life cycle. Lenacapasvir is the first drug approved to inhibit the HIV-1 capsid, providing a new treatment option for adults with multidrug-resistant HIV infection.
IC 50
HIV-1
Lenacapavir Preparation Products And Raw materials
Raw materials
Preparation Products
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Lenacapavir Suppliers
- Tel
- 18915538011; 18915538011
- liwei@boyanpharma.com
- Country
- China
- ProdList
- 109
- Advantage
- 58
- Tel
- 13656237714 13656237714;
- Fax
- 0512-65852853
- xiaokunfu@kyyykj.com
- Country
- China
- ProdList
- 295
- Advantage
- 55
- Tel
- 19353112242
- 1816280386@qq.com
- Country
- China
- ProdList
- 8045
- Advantage
- 58
- Tel
- hanfangpharma@126.com; 18616537568
- hanfangpharma@126.com
- Country
- China
- ProdList
- 29965
- Advantage
- 58
- Tel
- 13953971485
- 2199605322@qq.com
- Country
- China
- ProdList
- 200
- Advantage
- 58
- Tel
- 19231718652
- 278191416@qq.com
- Country
- China
- ProdList
- 482
- Advantage
- 58
- Tel
- 021-34975603-808 18721111801
- Fax
- +86-21-34975602-805
- sales@bocpharma.com
- Country
- China
- ProdList
- 1009
- Advantage
- 64
- Tel
- +21-18501659228 18501659228
- Fax
- sales@hope-chem.com
- info@hope-chem.com
- Country
- China
- ProdList
- 474
- Advantage
- 55
- Tel
- 18149758185
- sales-cpd@caerulumpharma.com
- Country
- China
- ProdList
- 3506
- Advantage
- 58
- Tel
- 20-66003216 18666003216
- Fax
- +86-20-28069063
- info@porsefinechemical.com
- Country
- China
- ProdList
- 1941
- Advantage
- 62
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View Lastest Price from Lenacapavir manufacturers
Shaanxi Dideu New Materials Co. Ltd
- Product
- Lenacapavir 2189684-44-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98
- Supply Ability
- 10000KGS
- Release date
- 2025-12-02
Jinan Jianfeng Chemical Co., Ltd
- Product
- GS-6207 2189684-44-2
- Price
- US $0.00/mg
- Min. Order
- 1mg
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2025-01-09
Jinan Jianfeng Chemical Co., Ltd
- Product
- Lenacapavir 2189684-44-2
- Price
- US $0.00-0.00/mg
- Min. Order
- 1mg
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2025-01-09