MARK4 inhibitor 1

Product Name: MARK4 inhibitor 1
CAS No.: 2271081-58-2
Chemical Name: MARK4 inhibitor 1
Synonyms: MARK4 inhibitor 1;(Z)-1-(4-Methoxybenzyl)-N'-(7-methyl-2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide;(Z)-1-(4-Methoxybenzyl)-N'-(7-methyl-2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide;Apoptosis,inhibit,AMPK,Inhibitor,AMP-activated protein kinase,MARK-4 inhibitor 1,MARK4 inhibitor 1;MARK4 inhibitor 1,(Z)-1-(4-methoxybenzyl)-N'-(7-methyl-2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide
CBNumber: CB05821202
Molecular Formula: C20H18N6O3
Formula Weight: 390.4
MOL File: 2271081-58-2.mol

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MARK4 inhibitor 1 Property

Melting point:: 313-316 °C
Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 5 mg/mL (12.81 mM; ultrasonic and adjust pH to 2 with HCl)
pka: 8.48±0.20(Predicted)
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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MARK4 inhibitor 1 Chemical Properties,Usage,Production

Uses

MARK4 inhibitor 1 is a potent and selective microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis[1].

References

[1] Aneja B, et al. Design and development of Isatin-triazole hydrazones as potential inhibitors of microtubule affinity-regulating kinase 4 for the therapeutic management of cell proliferation and metastasis. Eur J Med Chem. 2019 Feb 1;163:840-852. DOI:10.1016/j.ejmech.2018.12.026

MARK4 inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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MARK4 inhibitor 1 Suppliers

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2271081-58-2, MARK4 inhibitor 1Related Search:

MARK4 inhibitor 1

Apoptosis,inhibit,AMPK,Inhibitor,AMP-activated protein kinase,MARK-4 inhibitor 1,MARK4 inhibitor 1

(Z)-1-(4-Methoxybenzyl)-N'-(7-methyl-2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide

MARK4 inhibitor 1,(Z)-1-(4-methoxybenzyl)-N'-(7-methyl-2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide

(Z)-1-(4-Methoxybenzyl)-N'-(7-methyl-2-oxoindolin-3-ylidene)-1H-1,2,3-triazole-4-carbohydrazide

2271081-58-2