SHP836

Product Name: SHP836
CAS No.: 1957276-35-5
Chemical Name: SHP836
Synonyms: SHP836;SHP836,SHP-836;4-Pyrimidinamine, 5-(2,3-dichlorophenyl)-2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-, rel-
CBNumber: CB05821464
Molecular Formula: C16H19Cl2N5
Formula Weight: 352.26
MOL File: 1957276-35-5.mol

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SHP836 Property

Boiling point:: 526.8±60.0 °C(Predicted)
Density: 1.278±0.06 g/cm3(Predicted)
pka: 8.71±0.60(Predicted)
form: Solid
color: Light green to green

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0083598
Product name: SHP836
Purity: 99.59%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0083598
Product name: SHP836
Purity: 99.59%
Packaging: 10mg
Price: $580
Updated: 2021/12/16

ChemScene

Product number: CS-0083598
Product name: SHP836
Purity: 99.59%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0083598
Product name: SHP836
Purity: 99.59%
Packaging: 100mg
Price: $2550
Updated: 2021/12/16

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SHP836 Chemical Properties,Usage,Production

Uses

SHP836 is a SHP2 allosteric inhibitor, with an IC50 of 12 μM for the full length SHP2[1].

References

[1] Liu WS, et al. Structure based design of selective SHP2 inhibitors by De novo design, synthesis and biological evaluation. J Comput Aided Mol Des. 2019 Aug;33(8):759-774. DOI:10.1007/s10822-019-00213-z
[2] Garcia Fortanet J, et al. Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor. J Med Chem. 2016 Sep 8;59(17):7773-82. DOI:10.1021/acs.jmedchem.6b00680

SHP836 Preparation Products And Raw materials

Raw materials

Preparation Products

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SHP836 Suppliers

China 6 United States 3 Global 9

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
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TargetMol Chemicals Inc.

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Country: China
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Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
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RD International Technology Co., Limited

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Country: China
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

1957276-35-5, SHP836Related Search:

SHP836

SHP836,SHP-836

4-Pyrimidinamine, 5-(2,3-dichlorophenyl)-2-[(3R,5S)-3,5-dimethyl-1-piperazinyl]-, rel-

1957276-35-5