Mal-PEG2-CH2CH2COOtBu
- Product Name
- Mal-PEG2-CH2CH2COOtBu
- CAS No.
- 1374666-31-5
- Chemical Name
- Mal-PEG2-CH2CH2COOtBu
- Synonyms
- Mal-PEG2-C2-Boc;Mal-PEG-2-C2-Boc,PROTAC Linkers,Inhibitor,inhibit,Mal PEG2 C2 Boc,MalPEG2C2Boc;Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;Mal-PEG2-CH2CH2COOtBu/Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB05867105
- Molecular Formula
- C15H23NO6
- Formula Weight
- 313.35
- MOL File
- 1374666-31-5.mol
Mal-PEG2-CH2CH2COOtBu Property
- Boiling point:
- 428.7±30.0 °C(Predicted)
- Density
- 1.167±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- pka
- -2.34±0.20(Predicted)
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-21566
- Product name
- Mal-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $750
- Updated
- 2021/12/16
- Product number
- B-1562
- Product name
- Mal-PEG2-CH2CH2COOtBu
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $146.67
- Updated
- 2021/12/16
- Product number
- B-1562
- Product name
- Mal-PEG2-CH2CH2COOtBu
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $220
- Updated
- 2021/12/16
Mal-PEG2-CH2CH2COOtBu Chemical Properties,Usage,Production
Description
Mal-PEG2-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Uses
Mal-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Mal-PEG2-CH2CH2COOtBu Preparation Products And Raw materials
Raw materials
Preparation Products
Mal-PEG2-CH2CH2COOtBu Suppliers
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View Lastest Price from Mal-PEG2-CH2CH2COOtBu manufacturers
- Product
- MAL-PEG2-COOtBu 1374666-31-5
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-06
- Product
- Mal-PEG2-COOtBu 1374666-31-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-27