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Mal-PEG2-CH2CH2COOtBu

Product Name
Mal-PEG2-CH2CH2COOtBu
CAS No.
1374666-31-5
Chemical Name
Mal-PEG2-CH2CH2COOtBu
Synonyms
Mal-PEG2-C2-Boc;Mal-PEG-2-C2-Boc,PROTAC Linkers,Inhibitor,inhibit,Mal PEG2 C2 Boc,MalPEG2C2Boc;Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;Mal-PEG2-CH2CH2COOtBu/Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
CBNumber
CB05867105
Molecular Formula
C15H23NO6
Formula Weight
313.35
MOL File
1374666-31-5.mol
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Mal-PEG2-CH2CH2COOtBu Property

Boiling point:
428.7±30.0 °C(Predicted)
Density 
1.167±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Liquid
pka
-2.34±0.20(Predicted)
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-21566
Product name
Mal-PEG2-t-butylester
Purity
98%
Packaging
500mg
Price
$750
Updated
2021/12/16
Acrotein
Product number
B-1562
Product name
Mal-PEG2-CH2CH2COOtBu
Purity
97%
Packaging
0.25g
Price
$146.67
Updated
2021/12/16
Acrotein
Product number
B-1562
Product name
Mal-PEG2-CH2CH2COOtBu
Purity
97%
Packaging
0.5g
Price
$220
Updated
2021/12/16
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Mal-PEG2-CH2CH2COOtBu Chemical Properties,Usage,Production

Description

Mal-PEG2-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG2-CH2CH2COOtBu Preparation Products And Raw materials

Raw materials

Preparation Products

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Mal-PEG2-CH2CH2COOtBu Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
52923
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
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View Lastest Price from Mal-PEG2-CH2CH2COOtBu manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Mal-PEG2-COOtBu 1374666-31-5
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-27

1374666-31-5, Mal-PEG2-CH2CH2COOtBuRelated Search:


  • Mal-PEG2-C2-Boc
  • Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
  • Mal-PEG-2-C2-Boc,PROTAC Linkers,Inhibitor,inhibit,Mal PEG2 C2 Boc,MalPEG2C2Boc
  • Mal-PEG2-CH2CH2COOtBu/Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
  • 1374666-31-5