ChemicalBook > CAS DataBase List > LEM-14
LEM-14
- Product Name
- LEM-14
- CAS No.
- 1814881-70-3
- Chemical Name
- LEM-14
- Synonyms
- LEM-14;LEM-14, 10 mM in DMSO;[1]Benzothieno[2,3-d]pyrimidin-4(1H)-one, 2-[[4-[[(3R)-3,4-dihydro-1-oxo-1H-2-benzopyran-3-yl]carbonyl]-1-piperazinyl]methyl]-5,6,7,8-tetrahydro-;5-({4-[(3R)-1-oxo-3,4-dihydro-1H-2-benzopyran-3-carbonyl]piperazin-1-yl}methyl)-8-thia-4,6-diazatricyclo[7.4.0.02,?]trideca-1(9),2(7),4-trien-3-one
- CBNumber
- CB05867413
- Molecular Formula
- C25H26N4O4S
- Formula Weight
- 478.56
- MOL File
- 1814881-70-3.mol
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LEM-14 Property
- Boiling point:
- 788.3±70.0 °C(Predicted)
- Density
- 1.55±0.1 g/cm3(Predicted)
- form
- Solid
- pka
- 3.76±0.10(Predicted)
- color
- Light brown to gray
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N-Bromosuccinimide Price
DC Chemicals
- Product number
- DC12562
- Product name
- LEM-14
- Purity
- >98%
- Packaging
- 100mg
- Price
- $950
- Updated
- 2021/12/16
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LEM-14 Chemical Properties,Usage,Production
Uses
LEM-14 is a potent NSD2 inhibitor with an IC50 of 132 μM. LEM-14 has the potential for the research of multiple myeloma[1].
References
[1] Shen Y, et al. Identification of LEM-14 inhibitor of the oncoprotein NSD2. Biochem Biophys Res Commun. 2019 Jan 1;508(1):102-108. DOI:10.1016/j.bbrc.2018.11.037
LEM-14 Preparation Products And Raw materials
Raw materials
Preparation Products
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