ChemicalBook > CAS DataBase List > H-LYS-LYS-PRO-TYR-ILE-LEU-OH

H-LYS-LYS-PRO-TYR-ILE-LEU-OH

Product Name: H-LYS-LYS-PRO-TYR-ILE-LEU-OH
CAS No.: 139026-64-5
Chemical Name: H-LYS-LYS-PRO-TYR-ILE-LEU-OH
Synonyms: KKPYIL;LYS-LYS-PRO-TYR-ILE-LEU;[LYS8,9]-NEUROTENSIN (8-13);H-LYS-LYS-PRO-TYR-ILE-LEU-OH;(LYS8,LYS9)-NEUROTENSIN (8-13);Lys8,9]-Neurotensin (8-13),KKPYIL;[Lys8,9]-Neurotensin (8-13) - 5 mg;(lys-8-psi-ch2nh-lys9)-neurotensin*fragment 8-13;neurotensin, fragment 8-13, [Lys8-psi-(CH2NH)-Lys9];L-Leucine, L-lysyl-L-lysyl-L-prolyl-L-tyrosyl-L-isoleucyl-
CBNumber: CB0672069
Molecular Formula: C38H64N8O8
Formula Weight: 760.96
MOL File: 139026-64-5.mol

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H-LYS-LYS-PRO-TYR-ILE-LEU-OH Property

Boiling point:: 1109.7±65.0 °C(Predicted)
Density: 1.203±0.06 g/cm3(Predicted)
storage temp.: -15°C
pka: 3.41±0.10(Predicted)
form: Solid
color: White to off-white
Sequence: H-Lys-Lys-Pro-Tyr-Ile-Leu-OH

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: PEP0009203
Product name: (LYS8LYS9)-NEUROTENSIN(8-13)
Purity: 95.00%
Packaging: 1MG
Price: $606.38
Updated: 2021/12/16

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H-LYS-LYS-PRO-TYR-ILE-LEU-OH Chemical Properties,Usage,Production

Uses

[Lys8, Lys9]-Neurotensin (8-13) (JMV438), a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, with Ki values of 0.33 nM and 0.95 nM for hNTS1 and hNTS2 receptors, respectively[1].

References

[1] Emilie Eiselt, et al. Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia. ACS Chem Neurosci. 2019 Nov 20;10(11):4535-4544. DOI:10.1021/acschemneuro.9b00390

H-LYS-LYS-PRO-TYR-ILE-LEU-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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139026-64-5, H-LYS-LYS-PRO-TYR-ILE-LEU-OHRelated Search:

(LYS9,TRP11,GLU12)-NEUROTENSIN (8-13) (CYCLIC ANALOG) NEUROTENSIN (9-13) NEUROTENSIN (1-11) (BOC-LYS9)-NEUROTENSIN (9-13)-METHYL ESTER NEUROTENSIN (1-8) (DAB9)-NEUROTENSIN (8-13) NEUROTENSIN AC-ARG-ARG-PRO-TYR-ILE-LEU-OH NEUROTENSIN (1-6) NEUROTENSIN (8-13) H-LYS-LYS-PRO-TYR-ILE-LEU-OH JMV 449 NEUROTENSIN

(lys-8-psi-ch2nh-lys9)-neurotensin*fragment 8-13

neurotensin, fragment 8-13, [Lys8-psi-(CH2NH)-Lys9]

KKPYIL

H-LYS-LYS-PRO-TYR-ILE-LEU-OH

[LYS8,9]-NEUROTENSIN (8-13)

(LYS8,LYS9)-NEUROTENSIN (8-13)

LYS-LYS-PRO-TYR-ILE-LEU

L-Leucine, L-lysyl-L-lysyl-L-prolyl-L-tyrosyl-L-isoleucyl-

Lys8,9]-Neurotensin (8-13),KKPYIL

[Lys8,9]-Neurotensin (8-13) - 5 mg

139026-64-5

peptide