SENKTIDE

Product Name: SENKTIDE
CAS No.: 106128-89-6
Chemical Name: SENKTIDE
Synonyms: SENKTIDE;succinyl(asp6;Senktide?, BR;SENKTIDE (6-11);SUC-DF(ME)FGLM-NH2;SUC-DF-(NMEF)-GLM-NH2;M.W. 842.1 C40H55N7O11S;Senktide trifluoroacetate salt;Suc-Asp6, Me-Phe8] Substance P;Suc-[Asp6,MePhe8]substance P(6-11)
CBNumber: CB0679033
Molecular Formula: C40H55N7O11S
Formula Weight: 841.97
MOL File: 106128-89-6.mol

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SENKTIDE Property

Boiling point:: 1262.6±65.0 °C(Predicted)
Density: 1.290±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO : 50 mg/mL (59.38 mM; Need ultrasonic)
form: film
pka: 4.23±0.10(Predicted)
color: colorless

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0764
Product name: Senktide trifluoroacetate salt
Purity: ≥95% (HPLC)
Packaging: 500μg
Price: $134
Updated: 2024/03/01

Cayman Chemical

Product number: 16721
Product name: Senktide
Purity: ≥98%
Packaging: 500μg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 16721
Product name: Senktide
Purity: ≥98%
Packaging: 1mg
Price: $143
Updated: 2024/03/01

Cayman Chemical

Product number: 16721
Product name: Senktide
Purity: ≥98%
Packaging: 5mg
Price: $593
Updated: 2024/03/01

Tocris

Product number: 1068
Product name: Senktide
Packaging: 500U
Price: $129
Updated: 2021/12/16

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SENKTIDE Chemical Properties,Usage,Production

Uses

Senktide is a potent, selective agonist of the neuromedin K3 (NK3) receptor (EC50 = 0.5-3 nM). It less potently agonizes the NK1 receptor (EC50 = 35 μM) and is without effect on the NK2 receptor. Senktide is used to study the action of the NK3 receptor in cells and in animals.

Uses

Senktide is an NK3 agonist.

Biological Activity

Senktide is a selective Neurokinin NK3 tachykinin receptor agonist. Neurokinins (tachykinins) are members of a family of at least three neuropeptides, substance P, neurokinin A, and neurokinin B (NKB), with each mediating their biological effects through binding to a preferred G-protein-coupled receptor termed NK1, NK2, or NK3, respectively. All three NK receptors are expressed in regions of the central nervous system th at are related to emotion and cognition (i.e., amygdala and hippocampus) and have been linked to various degrees in psychiatric disorders. Neurokinin receptors, including NK3 receptors, are also expressed in the motor and sensory systems of the digestive tract.', 'Senktide treatment in follicular phase goats enhances the liberation of luteinizing hormone (LH) and advance the time of ovulation. Senktide has the ability to suppress gonadotropin-releasing hormone (GnRH) transcription. Treatment with senktide stimulates c-Fos and improve activator protein-1 (AP-1) activity.

storage

Store at -20°C

SENKTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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SENKTIDE Suppliers

China 76 France 1 Germany 2 Switzerland 1 United Kingdom 2 United States 16 USA 1 Global 99

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 1011
Advantage: 55

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9478
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-025-58361106-805-805 13082558573
Fax: 025-58361106-806
Email: liugang@njpeptide.com
Country: China
ProdList: 9980
Advantage: 55

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Fax: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7071
Advantage: 58

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View Lastest Price from SENKTIDE manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: SENKTIDE 106128-89-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-11

Career Henan Chemical Co

Product: SENKTIDE 106128-89-6
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-11

106128-89-6, SENKTIDERelated Search:

SUBSTANCE P (6-11) SENKTIDE, [PHE-3,4,5-3H]-,SENKTIDE, [PHENYLALANYL-3,4,5-3H]- 3-(4-methylphenyl)propan-1-amine SUBSTANCE P (7-11) CEGABA P-METHYLAMPHETAMINE SENKTIDE ANALOG (5-11),SENKTIDE ANALOG,NH2-SENKTIDE METHYL-(2-P-TOLYL-ETHYL)-AMINE SENKTIDE

succinyl(asp6

Substance P, fragment 6-11, succinyl[Asp6, NMePhe8]

M.W. 842.1 C40H55N7O11S

N-(3-Carboxy-1-oxopropyl)-L-Asp-L-Phe-N-methyl-L-Phe-Gly-L-Leu-L-Met-NH2

N-(3-Carboxy-1-oxopropyl)-L-αAsp-L-Phe-N-methyl-L-Phe-Gly-L-Leu-L-Met-NH2

Suc-[Asp6,MePhe8]substance P(6-11)

[SUCCINYL-ASP6,ME-PHE8] SUBSTANCE P

SUCCINYL-(ASP6,N-ME-PHE8)-SUBSTANCE P (6-11)

[SUCCINYL-ASP6 N-ME-PHE8]-SUBSTANCE P (6-11) (SENKTIDE)

[SUCCINYL-ASP6,N-ME-PHE8]-SUBSTANCE P, FRAGMENT 6-11

SUCCINYL-ASP-PHE-ME-PHE-GLY-LEU-MET-NH2

SUCCINYL-ASP-PHE-(N-ME)PHE-GLY-LEU-MET-NH2

SUCCINYL-ASP-PHE-N-METHYL-PHE-GLY-LEU-MET-NH2

SUC-ASP-PHE-N-ME-PHE-GLY-LEU-MET-NH2

SUC-[ASP6, N-ME-PHE8]-SUBSTANCE P (6-11)

SUBSTANCE P SUCCINYL-[ASP6, N-ME-PHE8]-FRAGMENT 6-11

SUC-DF(ME)FGLM-NH2

SUC-DF-(NMEF)-GLM-NH2

SENKTIDE

SENKTIDE (6-11)

SELECTIVE NEUROKININ B RECEPTOR PEPTIDE

Senktide?, BR

DFFGLM (Modifications: Asp-1 = Succinyl-Asp, Phe-3 = Me-Phe, Met-6 = C-terminal amide) trifluoroacetate salt

Senktide trifluoroacetate salt

Suc-Asp-Phe-MePhe-Gly-Leu-Met-NH2 trifluoroacetate salt

4-10-Neuromedin B (swine spinal cord), N-(3-carboxy-1-oxopropyl)-6-(N-methyl-L-phenylalanine)-7-de-L-valine-

L-Methioninamide, N-(3-carboxy-1-oxopropyl)-L-alpha-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-

N-(3-Carboxy-1-oxopropyl)-6-(N-methyl-L-phenylalanine)-7-de-L-valine-4-10-neuromedin B (swine spinal cord)

Substance p (6-11), succinyl-Asp(6)-me-Phe(8)-

Substance p (6-11), succinyl-aspartyl(6)-methylphenylalanine(8)-

Succinyl-6-Asp-8-me-Phe-substance p (6-11)

L-Methioninamide, N-(3-carboxy-1-oxopropyl)-L-α-aspartyl-L-phenylalanyl-N-methyl-L-phenylalanylglycyl-L-leucyl-

Senktide,Inhibitor,inhibit,Tachykinin receptor,NK receptor,Neurokinin Receptor

Suc-Asp6, Me-Phe8] Substance P

106128-89-6

C40H55N7O11S

BioChemical

Amino Acids and Peptides

Agonist

Biochemicals and Reagents

Tachykinins

Peptides

peptide

Tachykinin receptor