7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID
- Product Name
- 7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID
- CAS No.
- 1779-11-9
- Chemical Name
- 7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID
- Synonyms
- 2-amino-1-(6-bromophenyl)ethanol;7-bromo-3-hydroxy-2-naphthoic acid;3-Hydroxy-7-bromo-2-naphthoic acid;6-Bromo-2-naphthol-3-carboxylic Acid;7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBO;7-Bromo-3-hydroxy-2-naphthoic Acid >3-Isoxazolecarboxylicacid,5-(7-furanyl)-;7-bromo-3-hydroxy-2-naphthalenecarboxylicaci;7-bromo-3-hydroxynaphthalene-2-carboxylicaci;7-Bromo-3-hydroxy-2-naphthalenecarboxylic acid
- CBNumber
- CB0679806
- Molecular Formula
- C11H7BrO3
- Formula Weight
- 267.08
- MOL File
- 1779-11-9.mol
7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID Property
- Melting point:
- 262 °C
- Boiling point:
- 420.3±35.0 °C(Predicted)
- Density
- 1.772±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 2.81±0.30(Predicted)
- color
- White to Yellow
- BRN
- 2372925
- InChIKey
- XZWXQSGFZHRDNB-UHFFFAOYSA-N
- CAS DataBase Reference
- 1779-11-9
- EPA Substance Registry System
- 2-Naphthalenecarboxylic acid, 7-bromo-3-hydroxy- (1779-11-9)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 73178
- Product name
- 7-Bromo-3-hydroxy-2-naphthoic acid
- Purity
- ≥98.0% (HPLC), 98.0-102.0 wt. % (AT)
- Packaging
- 5g
- Price
- $100
- Updated
- 2025/07/31
- Product number
- 73178
- Product name
- 7-Bromo-3-hydroxy-2-naphthoic acid
- Purity
- ≥98.0% (HPLC), 98.0-102.0 wt. % (AT)
- Packaging
- 50g
- Price
- $325
- Updated
- 2025/07/31
- Product number
- B3180
- Product name
- 7-Bromo-3-hydroxy-2-naphthoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $29
- Updated
- 2025/07/31
- Product number
- B3180
- Product name
- 7-Bromo-3-hydroxy-2-naphthoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $67
- Updated
- 2025/07/31
- Product number
- FB149417
- Product name
- 7-Bromo-3-hydroxy-naphthalene-2-carboxylicacid
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production
Chemical Properties
Yellow solid
Synthesis Reference(s)
Journal of Medicinal Chemistry, 33, p. 171, 1990 DOI: 10.1021/jm00163a029
Synthesis
1779-10-8
1779-11-9
The general procedure for the synthesis of 3-hydroxy-7-bromo-2-naphthalenecarboxylic acid from 1,6-dibromo-2-hydroxynaphthalene-3-carboxylic acid was as follows: in a 1L three-necked flask, 40 g of 4,7-dibromo-3-hydroxy-2-naphthalenecarboxylic acid (0.116 mol) and 500 ml of glacial acetic acid were added, and the mixture was stirred thoroughly until uniform. Subsequently, 18 g of tin powder (0.153 mol) and 130 ml of concentrated hydrochloric acid were sequentially added to the reaction mixture. The reaction mixture was heated to 125°C and the reaction was refluxed at this temperature for 12 hours. After completion of the reaction, 300 ml of water was added to the mixture and cooled to room temperature with stirring. The reaction mixture was filtered and the filter cake was washed twice with 200 ml of water. Finally, the filter cake was dried in an oven to give 29.9 g of the target product 3-hydroxy-7-bromo-2-naphthalenecarboxylic acid in 96.5% yield.
References
[1] Patent: EP2573067, 2013, A1. Location in patent: Paragraph 0053; 0054
[2] Patent: CN106866433, 2017, A. Location in patent: Paragraph 0078; 0079; 0080
[3] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 14, p. 1021
[4] Proceedings - Indian Academy of Sciences, Section A, 1950, vol. 32, p. 292,298
[5] Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 19, p. 790
7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID manufacturers
- Product
- 7-BROMO-3-HYDROXY-NAPHTHALENE-2-CARBOXYLIC ACID 1779-11-9
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-10