FLUOROCHOLINE

Product Name: FLUOROCHOLINE
CAS No.: 459424-38-5
Chemical Name: FLUOROCHOLINE
Synonyms: FCH;FCH CHLORIDE;FLUOROCHOLINE;FLUOROCHLOLINE;FLUOROCHOLINE CHLORIDE;Choline chloride fluoride;FLUOROMETHYLCHOLINE CHLORIDE;Fluoromethylcholine Chloride (>2-fluorooxyethyl(trimethyl)ammonium;Fluoromethylcholine Chloride (>90%)
CBNumber: CB0688635
Molecular Formula: C5H13ClFNO
Formula Weight: 157.61
MOL File: 459424-38-5.mol

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FLUOROCHOLINE Property

Melting point:: 184-185
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Methanol (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
InChI: InChI=1S/C5H13FNO.ClH/c1-7(2,5-6)3-4-8;/h8H,3-5H2,1-2H3;1H/q+1;/p-1
InChIKey: QJEHIIJVWXGJAB-UHFFFAOYSA-M
SMILES: C(CO)[N+](C)(CF)C.[Cl-]
CAS DataBase Reference: 459424-38-5

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2922290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3490
Product name: FMC
Purity: ≥98% (HPLC)
Packaging: 25 mg
Price: $66.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML3490
Product name: FMC
Purity: ≥98% (HPLC)
Packaging: 100 mg
Price: $210
Updated: 2025/07/31

TRC

Product number: F598258
Product name: FluoromethylcholineChloride(>90%)
Packaging: 100mg
Price: $100
Updated: 2021/12/16

Matrix Scientific

Product number: 008941
Product name: Fluorocholine chloride
Packaging: 500mg
Price: $102
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4156-7-01
Product name: Fluorocholine chloride
Purity: 97%
Packaging: 1g
Price: $175
Updated: 2021/12/16

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FLUOROCHOLINE Chemical Properties,Usage,Production

Chemical Properties

Colourless crystals, very sensitive to moisture (hygroscopic)

Uses

Fluorocholine (chloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1].

Biological Activity

FMC is a monofluorinated choline th at acts as a nonlethal, mechanism-based irreversible inhibtor (pseudosubstrate-based suicide inhibitor) against gut anaerobic bacterial glycyl radical enzyme (GRE) cutC choline trimethylamine (TMA) lyase-catalyzed TMA production from choline (IC50 = 0.9 nM/P. mirabilis & 1.4 nM/D. alaskensis rec. CutC/D) without affecting the bacterial growth (P. mirabilis, E. fergusonii, and P. penneri). A single FMC oral dose (100 mg/kg) to mice on choline-supplemented diet significantly reduces plasma trimethylamine N-oxide (TMAO) level (up to 3 days) as well as diet-induced platelet responsiveness and thrombus formation without toxicity or increased bleeding risk.

References

[1] Bergmeyer H U, et al. Biochemical reagents[M]//Methods of Enzymatic Analysis. Academic Press, 1965: 967-1037.

FLUOROCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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FLUOROCHOLINE Suppliers

China 38 Germany 2 India 2 United Kingdom 2 United States 6 Global 50

United States Biological

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Combi-Blocks Inc.

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SynQuest Laboratories, Inc.

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Matrix Scientific

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INDOFINE Chemical Company, Inc.

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American Radiolabeled Chemicals, Inc.

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459424-38-5, FLUOROCHOLINERelated Search:

FLUOROCHOLINE FLUOROCHOLINE BROMIDE FLUOROCHOLINE FLUOROCHOLINE, [1,2-3H] CHLORIDE FLUOROCHOLINE, [1,2-14C] CHLORIDE

N,N-DIMETHYL-N-(FLUOROMETHYL) ETHANOLAMMONIUM CHLORIDE

ETHANAMINIUM, N-(FLUOROMETHYL)-2-HYDROXY-N,N-DIMETHYL-, CHLORIDE

DIMETHYL(FLUOROMETHYL)(2-HYDROXYETHYL)AMMONIUM CHLORIDE

2-fluorooxyethyl(trimethyl)ammonium

N-(fluoromethyl)-2-hydroxy-N,N-dimethylethan-1-aminium chloride

FCH

FCH CHLORIDE

FLUOROMETHYLCHOLINE CHLORIDE

FLUOROCHOLINE CHLORIDE

FLUOROCHLOLINE

FLUOROCHOLINE

Dimethyl(fluoromethyl)(2-hydroxyethyl)ammonium chloride, N,N-Dimethyl-N-(fluoromethyl)-2-hydroxyethanaminium chloride

N-(Fluoromethyl)-2-hydroxy-N,N-dimethylethanaminium chloride

Choline chloride fluoride

Fluoromethylcholine Chloride (&gt

Fluoromethylcholine Chloride (>90%)

fluoromethyl-(2-hydroxyethyl)-dimethylazanium

459424-38-5

C5H13FNOCl

C5H13ClFNO