ChemicalBook > CAS DataBase List > 3,7-DIMETHYL-1-PROPARGYLXANTHINE

3,7-DIMETHYL-1-PROPARGYLXANTHINE

Product Name
3,7-DIMETHYL-1-PROPARGYLXANTHINE
CAS No.
14114-46-6
Chemical Name
3,7-DIMETHYL-1-PROPARGYLXANTHINE
Synonyms
DMPX;Nsc 242985;-1H-purine-2,6(3H,7H);Zolpidem Impurity 2-d6;3,7-Dimethyl-1-(prop-2-yn-1-yl);3,7-DIMETHYL-1-PROPARGYLXANTHINE;1-(2-Propynyl)-3,7-dimethylxanthine;3,7-DIMETHYL-1-(2-PROPYNYL)XANTHINE;DMPX, 3,7-Dimethyl-1-(2-propynyl)xanthine;3,7-Dimethyl-1-(2-propynyl)xanthine, DMPX
CBNumber
CB0688675
Molecular Formula
C10H10N4O2
Formula Weight
218.21
MOL File
14114-46-6.mol
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3,7-DIMETHYL-1-PROPARGYLXANTHINE Property

Melting point:
204-205°C
storage temp. 
-20°C Freezer
solubility 
DMSO: ≥15 mg/mL
form 
solid
color 
white
CAS DataBase Reference
14114-46-6
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D134
Product name
3,7-Dimethyl-1-propargylxanthine
Purity
≥98% (HPLC), powder
Packaging
10mg
Price
$276
Updated
2024/03/01
Sigma-Aldrich
Product number
D134
Product name
3,7-Dimethyl-1-propargylxanthine
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$526
Updated
2024/03/01
TRC
Product number
D477850
Product name
3,7-Dimethyl-1-propargylxanthine
Packaging
5mg
Price
$130
Updated
2021/12/16
Usbiological
Product number
D3693-55
Product name
3,7-Dimethyl-1-propargylxanthine
Packaging
10mg
Price
$460
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0004478
Product name
3,7-DIMETHYL-1-PROPARGYLXANTHINE
Purity
95.00%
Packaging
5MG
Price
$496.84
Updated
2021/12/16
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3,7-DIMETHYL-1-PROPARGYLXANTHINE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

A selective A2 adenosine receptor antagonist. Pharmacology: Ki vs [3H]NECA at A2 receptors in rat striatal membranes: 11± 3 uM; Ki vs [3H]CHA at A1 receptors in rat cerebral cortical membranes: 45 ± 4 uM.

Uses

3,7-Dimethyl-1-propargylxanthine (DMPX) has been used as an A2 -adenosine receptor (AR) antagonist:

  • to study its effects on potential modulation of motor output elicited by epidural spinal stimulation (ESS)
  • to study the role of A2a?receptor in elevating cyclic adenosine monophosphate (cAMP) levels
  • to study its effects on the cell viability of human gastric cancer cell line

Biochem/physiol Actions

3,7-Dimethyl-1-propargylxanthine (DMPX) is a caffeine analog and A2-selective adenosine receptor (AR) antagonist.

3,7-DIMETHYL-1-PROPARGYLXANTHINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3,7-DIMETHYL-1-PROPARGYLXANTHINE Suppliers

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14114-46-6, 3,7-DIMETHYL-1-PROPARGYLXANTHINERelated Search:

7-methyl-8-(3-bromostyryl)-3,7-dimethyl-1-propargylxanthine 1,7-DIMETHYL-3-PROPARGYLXANTHINE 1,3-Dimethyl-7-propargylxanthine MSX-2 3-HYDROXYPROPYL-7-METHYL-8-(3-METHOXYSTYRYL)-1-PROPARGYLXANTHINE, [METHYL-3H] 3,7-DIMETHYL-1-PROPARGYLXANTHINE 1,7-DIMETHYLXANTHINE CAFFEINE N-PROP-2-YNYLUREA THEOBROMINE

  • DMPX
  • 3,7-DIMETHYL-1-PROPARGYLXANTHINE
  • 3,7-DIMETHYL-1-(2-PROPYNYL)XANTHINE
  • 3,7-DIMETHYL-1-PROPARGYLXANTHINE (DMPX) ADENOSINE ANTAGONIST
  • DMPX, 3,7-Dimethyl-1-(2-propynyl)xanthine
  • 3,7-Dimethyl-1-(2-propynyl)xanthine, DMPX
  • 1-(2-Propynyl)-3,7-dimethyl-7H-purine-2,6(1H,3H)-dione
  • 1-(2-Propynyl)-3,7-dimethylxanthine
  • 3,7-Dimethyl-1-(2-propynyl)-7H-purine-2,6(1H,3H)-dione
  • 1H-Purine-2,6-dione, 3,7-dihydro-3,7-dimethyl-1-(2-propynyl)-
  • Nsc 242985
  • 3,7-Dimethyl-1-propargylxanthine,3,7-Dimethyl-1-(2-propynyl)xanthine, DMPX
  • 3,7-diMethyl-1-(prop-2-yn-1-yl)-1H-purine-2,6(3H,7H)-dione
  • -1H-purine-2,6(3H,7H)
  • 3,7-Dimethyl-1-(prop-2-yn-1-yl)
  • 1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(2-propyn-1-yl)-
  • Zolpidem Impurity 2-d6
  • 14114-46-6
  • 14114-46-4
  • All Inhibitors
  • Inhibitors
  • Heterocycles