2,3,5-TRIMETHYLANISOLE

Product Name: 2,3,5-TRIMETHYLANISOLE
CAS No.: 20469-61-8
Chemical Name: 2,3,5-TRIMETHYLANISOLE
Synonyms: Trimethylanisole;Acitretin Impurity 4;2,3,5-TRIMETHYLANISOLE;2,3,5-TRIMETHYLANISOLE 99%;2,3,5-Trimethylanisole,99%;1-METHOXY-2,3,5-TRIMETHYL-BENZENE;Benzene, 1-methoxy-2,3,5-trimethyl-
CBNumber: CB0699640
Molecular Formula: C10H14O
Formula Weight: 150.22
MOL File: 20469-61-8.mol

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2,3,5-TRIMETHYLANISOLE Property

Boiling point:: 213-216 °C
Density: 0.97
refractive index: 1.518-1.52
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform, Dichloromethane, Tetrahydrofuran
form: Oil
color: Colourless
LogP: 3.510 (est)
CAS DataBase Reference: 20469-61-8(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
Hazard Note: Irritant
HS Code: 29093090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: T2456
Product name: 2,3,5-Trimethylanisole
Purity: >97.0%(GC)
Packaging: 5g
Price: $57
Updated: 2025/07/31

TRC

Product number: M269750
Product name: 1-Methoxy-2,3,5-trimethylbenzene
Packaging: 250mg
Price: $50
Updated: 2021/12/16

Usbiological

Product number: M3292-53
Product name: 1-Methoxy-2,3,5-trimethylbenzene
Packaging: 2.5g
Price: $425
Updated: 2021/12/16

TRC

Product number: M269750
Product name: 1-Methoxy-2,3,5-trimethylbenzene
Packaging: 25g
Price: $545
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0007839
Product name: 2,3,5-TRIMETHYLANISOLE
Purity: 95.00%
Packaging: 500MG
Price: $721.88
Updated: 2021/12/16

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2,3,5-TRIMETHYLANISOLE Chemical Properties,Usage,Production

Chemical Properties

Colourless Oil

Uses

1-Methoxy-2,3,5-trimethylbenzene (cas# 20469-61-8) is a compound useful in organic synthesis.

Synthesis

697-82-5

616-38-6

20469-61-8

General procedure: Alkylation reaction of 2,3,5-trimethylphenol using dimethyl carbonate. The specific operation was as follows: 3 mmol of Mn2(CO)10, W(CO)6 or Co2(CO)8 catalyst, 100 mmol of 2,3,5-trimethylphenol, and 300 mmol of dimethyl carbonate were sequentially added to a 17 mL stainless steel high-pressure micro reactor. After sealing the reactor, it was heated at 180°C for 1 hour. Upon completion of the reaction, the reactor was cooled to room temperature and opened, and the reaction mixture was filtered through an alumina layer. Subsequently, the unreacted dimethyl carbonate was removed by distillation, and the residue was distilled under atmospheric or reduced pressure conditions or recrystallized using ethanol to give 1-methoxy-2,3,5-trimethylbenzene. The compound was obtained in 99% yield with a boiling point of 84.5-85 °C (7 mmHg).13C NMR data were as follows (δC, ppm): 11.60, 20.03, 21.38 (CH3); 110.52 (C6), 119.95 (C2), 124.92 (C4), 137.32 (C3), 137.54 (C5). 157.43 (C1). Elemental analysis results: measured value (%): C 79.87; H 9.35. Calculated value (%) for molecular formula C10H14O: C 79.96; H 9.39.

References

[1] Russian Journal of Organic Chemistry, 2015, vol. 51, # 3, p. 330 - 334
[2] Methylation of Phenol and Its Derivatives with Dimethyl Carbonate in the Presence of Mn2(CO)10, W(CO)6, and Co2(CO)8, 2015, vol. 51, # 3, p. 330 - 334,5

2,3,5-TRIMETHYLANISOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3,5-TRIMETHYLANISOLE Suppliers

Belgium 1 Canada 1 China 93 Europe 2 Germany 1 India 4 Japan 3 United Kingdom 6 United States 19 USA 1 Global 131

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View Lastest Price from 2,3,5-TRIMETHYLANISOLE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2,3,5-TRIMETHYLANISOLE 20469-61-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

20469-61-8, 2,3,5-TRIMETHYLANISOLERelated Search:

N-Fmoc-N'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine 2,2,5,7,8-PENTAMETHYLCHROMAN-6-SULFONYL CHLORIDE Vitamin E nicotinate 4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE 5,7-DIMETHYLCHROMONE-3-CARBOXALDEHYDE Trolox FUMARPROTOCETRARIC ACID H-ARG(MTR)-OH Z-ARG(MTR)-OH CHA N-Fmoc-N'-(4-methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine DL-ALPHA-TOCOPHEROL HYDROGEN SUCCINATE BOC-ARG(MTS)-OH 2,3,6-Trimethylanisole STICTIC ACID Fmoc-L-Arg(Pmc)-OH 2,4,6-TRIMETHYLANISOLE 5-(CHLOROMETHYL)MECONIN LABOTEST-BB LT00452283

2,3,5-Trimethylanisole,99%

Trimethylanisole

2,3,5-TRIMETHYLANISOLE 99%

2,3,5-TRIMETHYLANISOLE

1-METHOXY-2,3,5-TRIMETHYL-BENZENE

Acitretin Impurity 4

Benzene, 1-methoxy-2,3,5-trimethyl-

20469-61-8

Aromatics Compounds

Anisoles, Alkyloxy Compounds & Phenylacetates

Aromatics

Intermediates