(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE

Product Name: (3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE
CAS No.: 135911-02-3
Chemical Name: (3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE
Synonyms: Rp 68651;RP 67580;7,7-Diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one;(3aR,7aR)-Octahydro-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyl-4H-isoindol;(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE;(3aR,7aR)-2-(1-Imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenylhexahydro-1H-isoindol-4(2H)-one;4H-Isoindol-4-one, octahydro-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyl-, (3ar-cis)-;4H-Isoindol-4-one, octahydro-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyl-, (3ar,7ar)-
CBNumber: CB0709086
Molecular Formula: C29H30N2O2
Formula Weight: 438.56
MOL File: 135911-02-3.mol

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(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE Property

storage temp.: Store at +4°C
solubility: Soluble to 100 mM in ethanol and to 50 mM in DMSO
form: Powder

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1635
Product name: RP67580
Purity: ≥97%(HPLC)
Packaging: 10
Price: $233
Updated: 2021/12/16

Tocris

Product number: 1635
Product name: RP67580
Purity: ≥97%(HPLC)
Packaging: 50
Price: $952
Updated: 2021/12/16

Usbiological

Product number: 256506
Product name: RP 67580
Packaging: 10mg
Price: $480
Updated: 2021/12/16

TRC

Product number: R700993
Product name: RP67580
Packaging: 10mg
Price: $750
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD157381
Product name: 7,7-Diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one
Packaging: 5mg
Price: $178.5
Updated: 2021/12/16

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(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE Chemical Properties,Usage,Production

Uses

RP 67580 is a neurokinin-1 receptor (NK1) antagonist.

Biological Activity

Potent and selective tachykinin NK 1 receptor antagonist (K i values are 2.9 nM and > 10 μ M for rat NK 1 , and rat NK 2 and NK 3 receptors respectively). Displays higher affinity at rat and mouse than human receptors. Antinociceptive in vivo , possibly partly via inhibition of calcium channels.

storage

Store at -20°C

(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE Suppliers

China 19 Europe 1 Germany 2 United Kingdom 3 United States 7 USA 1 Global 33

3B Pharmachem (Wuhan) International Co.,Ltd.

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135911-02-3, (3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONERelated Search:

1-(DIETHYLAMINO)PENTAN-3-ONE cis-Octahydroisoindole 4,4-DIPHENYLCYCLOHEXANONE 4-Phenylcyclohexanone (3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE 2-[(dimethylamino)methyl]cyclohexan-1-one RP67580, [METHOXYPHENYL-3,5-3H]-

RP 67580

(3aR,7aR)-Octahydro-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyl-4H-isoindol

4H-Isoindol-4-one, octahydro-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyl-, (3ar,7ar)-

4H-Isoindol-4-one, octahydro-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyl-, (3ar-cis)-

7,7-Diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

(3AR,7AR)-OCTAHYDRO-2-[1-IMINO-2-(2-METHOXYPHENYL)ETHYL]-7,7-DIPHENYL-4H-ISOINDOL-4-ONE

Rp 68651

(3aR,7aR)-2-(1-Imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenylhexahydro-1H-isoindol-4(2H)-one

135911-02-3

C29H30N2O2

Tachykinin receptor