Autogramin-1

Product Name: Autogramin-1
CAS No.: 2375541-73-2
Chemical Name: Autogramin-1
Synonyms: Autogramin-1;Autogramin-1, 10 mM in DMSO;Inhibitor,inhibit,Autogramin1,Autogramin-1,Autophagy,Autogramin 1;tert-butyl 2-(2,4-dioxo-3-propyl-1,2,3,4-tetrahydroquinazoline-7-carboxamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate;Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-[[(1,2,3,4-tetrahydro-2,4-dioxo-3-propyl-7-quinazolinyl)carbonyl]amino]-, 1,1-dimethylethyl ester
CBNumber: CB07247211
Molecular Formula: C23H27N5O5S
Formula Weight: 485.56
MOL File: 2375541-73-2.mol

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Autogramin-1 Property

Density: 1.359±0.06 g/cm3(Predicted)
pka: 6.67±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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Autogramin-1 Chemical Properties,Usage,Production

Uses

Autogramin-1 potently inhibits autophagy induced by either starvation (IC50=0.17 μM) or mTORC1 inhibition (Rapamycin; IC50=0.44 μM)[1].

References

[1] Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720. DOI:10.1038/s41589-019-0307-5

Autogramin-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Autogramin-1 Suppliers

China 29 United States 3 Global 32

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2375541-73-2, Autogramin-1Related Search:

Autogramin-1

Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-2-[[(1,2,3,4-tetrahydro-2,4-dioxo-3-propyl-7-quinazolinyl)carbonyl]amino]-, 1,1-dimethylethyl ester

tert-butyl 2-(2,4-dioxo-3-propyl-1,2,3,4-tetrahydroquinazoline-7-carboxamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

Inhibitor,inhibit,Autogramin1,Autogramin-1,Autophagy,Autogramin 1

Autogramin-1, 10 mM in DMSO

2375541-73-2