ChemicalBook > CAS DataBase List > 12(S)-HHT

12(S)-HHT

Product Name
12(S)-HHT
CAS No.
54397-84-1
Chemical Name
12(S)-HHT
Synonyms
12-HHT;12-HHTRE;12(S)-HHT;12(S)-HHTRE;12(S)-HHTrE (12(S)-HHT);KUKJHGXXZWHSBG-WBGSEQOASA-N;12(S)-HHTrE Lipid Maps MS Standard;12-HYDROXY-HEPTA- DECATRIENOIC ACID;12(S)-HYDROXYHEPTADECA-5Z,8E,10E-TRIENOIC ACID;12(S)-hydroxy-5(Z),8(E),10(E)-*heptadecatrienoic
CBNumber
CB0726021
Molecular Formula
C17H28O3
Formula Weight
280.4
MOL File
54397-84-1.mol
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12(S)-HHT Property

Boiling point:
451.8±45.0 °C(Predicted)
Density 
0.992±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form 
ethanol solution
pka
4.75±0.10(Predicted)
color 
Colorless to light yellow
biological source
synthetic (organic)
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Safety

Hazard Codes 
F,Xi
Risk Statements 
11-36/37/38
Safety Statements 
16-26-36
RIDADR 
UN 1170 3/PG 2
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H1640
Product name
12(S)-Hydroxy-(5Z,8E,10E)-heptadecatrienoic acid
Purity
≥93% (HPLC), ethanol solution
Packaging
50μg
Price
$258
Updated
2024/03/01
Cayman Chemical
Product number
34590
Product name
12(S)-HHTrE
Purity
≥95%
Packaging
25μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
34590
Product name
12(S)-HHTrE
Purity
≥95%
Packaging
50μg
Price
$230
Updated
2024/03/01
Cayman Chemical
Product number
34590
Product name
12(S)-HHTrE
Purity
≥95%
Packaging
100μg
Price
$433
Updated
2024/03/01
Cayman Chemical
Product number
34590
Product name
12(S)-HHTrE
Purity
≥95%
Packaging
250μg
Price
$961
Updated
2024/03/01
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12(S)-HHT Chemical Properties,Usage,Production

Uses

12(S)-HHTrE is an unusual product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of the human platelet. It is biosynthesized by thromboxane synthase (TX synthase) from prostaglandin H2 (PGH2) concurrently with TXA2. The biological role of 12(S)-HHTrE is uncertain. It is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH.

Uses

12(S)-HHTrE is a metabolite of arachidonic acid (A765000), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.

Definition

ChEBI: A trienoic fatty acid that consists of (5Z,8E,10E)-heptadeca-5,8,10-trienoic acid bearing an additional 12S-hydroxy substituent.

12(S)-HHT Preparation Products And Raw materials

Raw materials

Preparation Products

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12(S)-HHT Suppliers

Shanghai Boyle Chemical Co., Ltd.
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54397-84-1, 12(S)-HHTRelated Search:


  • (12S,5Z,8E,10E)-12-Hydroxy-5,8,10-heptadecatrienoic acid
  • (5Z,8E,10E,12S)-12-Hydroxy-5,8,10-heptadecatrienoic acid
  • 12(S)-HHTrE Lipid Maps MS Standard
  • KUKJHGXXZWHSBG-WBGSEQOASA-N
  • 12(S)-hydroxy-5(Z),8(E),10(E)-*heptadecatrienoic
  • 12(S)-HYDROXY-5(Z),8(E),10(E)-*HEPTADECA TRIENOIC AC
  • 12(S)-HYDROXYHEPTADECA-5Z,8E,10E-TRIENOIC ACID
  • 12(S)-HYDROXY-(5Z,8E,10E)-HEPTADECATRIENOIC ACID
  • 12(S)-HHT
  • 12(S)-HHTRE
  • 12-HYDROXY-HEPTA- DECATRIENOIC ACID
  • 12-HHT
  • 12-HHTRE
  • 5,8,10-Heptadecatrienoic acid, 12-hydroxy-, (5Z,8E,10E,12S)-
  • 12(S)-HHTrE (12(S)-HHT)
  • 12(S)-Hydroxy-(5Z,8E,10E)-heptadecatrienoic acid >=93% (HPLC), ethanol solution
  • 54397-84-1
  • C17H28O3
  • Biochemicals and Reagents
  • BioChemical
  • Fatty Acids
  • Hydroxy fatty acids
  • Lipids
  • Polyunsaturated
  • Unsaturated fatty acids and derivatives