12(S)-HHT

Product Name: 12(S)-HHT
CAS No.: 54397-84-1
Chemical Name: 12(S)-HHT
Synonyms: 12-HHT;12-HHTRE;12(S)-HHT;12(S)-HHTRE;12(S)-HHTrE (12(S)-HHT);KUKJHGXXZWHSBG-WBGSEQOASA-N;12(S)-HHTrE Lipid Maps MS Standard;12-HYDROXY-HEPTA- DECATRIENOIC ACID;12(S)-HYDROXYHEPTADECA-5Z,8E,10E-TRIENOIC ACID;12(S)-hydroxy-5(Z),8(E),10(E)-*heptadecatrienoic
CBNumber: CB0726021
Molecular Formula: C17H28O3
Formula Weight: 280.4
MOL File: 54397-84-1.mol

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12(S)-HHT Property

Boiling point:: 451.8±45.0 °C(Predicted)
Density: 0.992±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
form: ethanol solution
pka: 4.75±0.10(Predicted)

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Safety

Hazard Codes: F,Xi
Risk Statements: 11-36/37/38
Safety Statements: 16-26-36
RIDADR: UN 1170 3/PG 2
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H1640
Product name: 12(S)-Hydroxy-(5Z,8E,10E)-heptadecatrienoic acid
Purity: ≥93% (HPLC), ethanol solution
Packaging: 50μg
Price: $258
Updated: 2024/03/01

Cayman Chemical

Product number: 34590
Product name: 12(S)-HHTrE
Purity: ≥95%
Packaging: 25μg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 34590
Product name: 12(S)-HHTrE
Purity: ≥95%
Packaging: 50μg
Price: $230
Updated: 2024/03/01

Cayman Chemical

Product number: 34590
Product name: 12(S)-HHTrE
Purity: ≥95%
Packaging: 100μg
Price: $433
Updated: 2024/03/01

Cayman Chemical

Product number: 34590
Product name: 12(S)-HHTrE
Purity: ≥95%
Packaging: 250μg
Price: $961
Updated: 2024/03/01

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12(S)-HHT Chemical Properties,Usage,Production

Uses

12(S)-HHTrE is an unusual product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of the human platelet. It is biosynthesized by thromboxane synthase (TX synthase) from prostaglandin H2 (PGH2) concurrently with TXA2. The biological role of 12(S)-HHTrE is uncertain. It is avidly oxidized to 12-oxoHTrE by porcine 15-hydroxy PGDH.

Uses

12(S)-HHTrE is a metabolite of arachidonic acid (A765000), which is an essential fatty acid and a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and Arachidonic Acid is also a constituent of animal phosphatides.

Definition

ChEBI: A trienoic fatty acid that consists of (5Z,8E,10E)-heptadeca-5,8,10-trienoic acid bearing an additional 12S-hydroxy substituent.

12(S)-HHT Preparation Products And Raw materials

Raw materials

Preparation Products

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12(S)-HHT Suppliers

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54397-84-1, 12(S)-HHTRelated Search:

2,4-HEPTADIEN-1-OL 1,3,6-HEPTATRIENE 12(S)-HHT

(12S,5Z,8E,10E)-12-Hydroxy-5,8,10-heptadecatrienoic acid

(5Z,8E,10E,12S)-12-Hydroxy-5,8,10-heptadecatrienoic acid

12(S)-HHTrE Lipid Maps MS Standard

KUKJHGXXZWHSBG-WBGSEQOASA-N

12(S)-hydroxy-5(Z),8(E),10(E)-*heptadecatrienoic

12(S)-HYDROXY-5(Z),8(E),10(E)-*HEPTADECA TRIENOIC AC

12(S)-HYDROXYHEPTADECA-5Z,8E,10E-TRIENOIC ACID

12(S)-HYDROXY-(5Z,8E,10E)-HEPTADECATRIENOIC ACID

12(S)-HHT

12(S)-HHTRE

12-HYDROXY-HEPTA- DECATRIENOIC ACID

12-HHT

12-HHTRE

5,8,10-Heptadecatrienoic acid, 12-hydroxy-, (5Z,8E,10E,12S)-

12(S)-HHTrE (12(S)-HHT)

12(S)-Hydroxy-(5Z,8E,10E)-heptadecatrienoic acid >=93% (HPLC), ethanol solution

54397-84-1

C17H28O3

Biochemicals and Reagents

BioChemical

Fatty Acids

Hydroxy fatty acids

Lipids

Polyunsaturated

Unsaturated fatty acids and derivatives