ChemicalBook > CAS DataBase List > H-VAL-PRO-LEU-OH

H-VAL-PRO-LEU-OH

Product Name
H-VAL-PRO-LEU-OH
CAS No.
90614-49-6
Chemical Name
H-VAL-PRO-LEU-OH
Synonyms
DIPROTIN B;VAL-PRO-LEU;Val-Pro-Leu-OH;H-VAL-PRO-LEU-OH;L-Val-L-Pro-L-Leu-OH;L-VALYL-L-PROLYL LEUCINE;(-)-L-Val-L-Pro-L-Leu-OH;L-Leucine,L-valyl-L-prolyl-;n-(1-l-valyl-l-prolyl)-l-leucin;2-[[1-(2-amino-3-methylbutanoyl)pyrrolidine-2-carbonyl]amino]-4-methylpentanoic acid
CBNumber
CB0731342
Molecular Formula
C16H29N3O4
Formula Weight
327.42
MOL File
90614-49-6.mol
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H-VAL-PRO-LEU-OH Property

Boiling point:
575.9±50.0 °C(Predicted)
Density 
1.157±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
form 
White lyophilized powder.
pka
3.71±0.21(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
D3750-01
Product name
Diprotin B
Packaging
1mg
Price
$531
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD109478
Product name
Diprotin B H-Val-Pro-Leu-OH
Packaging
250mg
Price
$822.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD109478
Product name
Diprotin B H-Val-Pro-Leu-OH
Packaging
25mg
Price
$136
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD109478
Product name
Diprotin B H-Val-Pro-Leu-OH
Packaging
50mg
Price
$236
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD109478
Product name
Diprotin B H-Val-Pro-Leu-OH
Packaging
100mg
Price
$411
Updated
2021/12/16
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H-VAL-PRO-LEU-OH Chemical Properties,Usage,Production

Uses

Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue[1][2].

Definition

ChEBI: Val-Pro-Leu is an oligopeptide.

References

[1] Rahfeld J, et al. Are diprotin A (Ile-Pro-Ile) and diprotin B (Val-Pro-Leu) inhibitors or substrates of dipeptidyl peptidase IV? Biochim Biophys Acta. 1991 Jan 29;1076(2):314-6. DOI:10.1016/0167-4838(91)90284-7
[2] Hatanaka T, et al. Inhibitory effect of collagen-derived tripeptides on dipeptidylpeptidase-IV activity. J Enzyme Inhib Med Chem. 2014 Dec;29(6):823-8. DOI:10.3109/14756366.2013.858143

H-VAL-PRO-LEU-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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90614-49-6, H-VAL-PRO-LEU-OHRelated Search:

DIPROTIN A AC-GLY-LEU-OH 2-(Aminomethyl)-1-ethylpyrrolidine Gly-Gly-Leu (S)-2-AMINO-3-METHYL-1-(PYRROLIDIN-1-YL)BUTAN-1-ONE H-ALA-PRO-GLY-OH H-GLY-ALA-LEU-OH H-GLY-PRO-GLY-OH H-VAL-PRO-LEU-OH H-VAL-GLY-GLY-OH H-ALA-PRO-ALA-OH H-ALA-PRO-LEU-OH H-GLY-PRO-ALA-OH ESTHPRISSEVHIPL H-PRO-LEU-OH ETHYL[(1-PROPYLPYRROLIDIN-2-YL)METHYL]AMINE N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-1-PROPANAMINE (1-BUTYL-2-PYRROLIDINYL)-N-METHYLMETHANAMINE

  • H-VAL-PRO-LEU-OH
  • DIPROTIN B
  • L-VALYL-L-PROLYL LEUCINE
  • VAL-PRO-LEU
  • n-(1-l-valyl-l-prolyl)-l-leucin
  • (-)-L-Val-L-Pro-L-Leu-OH
  • L-Val-L-Pro-L-Leu-OH
  • Val-Pro-Leu-OH
  • 2-[[1-(2-amino-3-methylbutanoyl)pyrrolidine-2-carbonyl]amino]-4-methylpentanoic acid
  • L-Leucine,L-valyl-L-prolyl-
  • 90614-49-6
  • C16H29N3O4
  • Antibiotics