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Beta-Neoendorphin

Product Name
Beta-Neoendorphin
CAS No.
77739-21-0
Chemical Name
Beta-Neoendorphin
Synonyms
B-neoendorphin;β-Neo-Endorphin;sh-Nonapeptide-3;BETA-NEOENDORPHIN;β-Neoendorphin (human);β-Neo-Endorphin (Porcine);BETA-NEO-ENDORPHIN (PORCINE);b-Neoendorphin (human) (9CI);TYR-GLY-GLY-PHE-LEU-ARG-LYS-TYR-PRO;PRODYNORPHIN (175-183) (HUMAN, PORCINE)
CBNumber
CB0758529
Molecular Formula
C54H77N13O12
Formula Weight
1100.27
MOL File
77739-21-0.mol
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Beta-Neoendorphin Property

storage temp. 
-15°C
form 
Solid
color 
White to off-white
InChIKey
RTXIYIQLESPXIV-VLOLPVCOSA-N
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb364369
Product name
Beta-Neo-Endorphin
Purity
> 95%
Packaging
1mg
Price
$287.3
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BIO0000362
Product name
BETA-NEOENDORPHIN
Purity
95.00%
Packaging
5MG
Price
$500.28
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364369
Product name
Beta-Neo-Endorphin
Purity
> 95%
Packaging
5mg
Price
$552.5
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364369
Product name
Beta-Neo-Endorphin
Purity
> 95%
Packaging
10mg
Price
$708.9
Updated
2021/12/16
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Beta-Neoendorphin Chemical Properties,Usage,Production

Uses

β-Neo-Endorphin is an endogenous opioid peptide. β-Neo-Endorphin is a hypothalamic “big” Leu-enkephalin of porcine origin. β-Neo-Endorphin shows activation of the Erk1/2, MMP-2 and MMP-9[1][2].

Definition

Pro-dynorphin (also referred to as pro-enkephalin B) can be processed to produce dynorphin A, dynorphin B, α-neoendorphin, and β-neoendorphin. Beta-Neoendorphin is an endogenous opioid peptide. Beta-Neoendorphin is a hypothalamic “big” Leu-enkephalin of porcine origin. It shows activation of the Erk1/2, MMP-2 and MMP-9. The carboxypeptidase cleavage step is not rate limiting for the production of most neuroendocrine peptides, the exceptions being the conversion of α-neoendorphin into β-neoendorphin, which requires cleavage of a Pro-Lys bond, and the generation of rat β-endorphin 1-26, which requires cleavage of a C-terminal His-27 residue.

IC 50

ERK1; ERK2; MMP-2; MMP-9

References

[1] Minamino N, et al. Beta-neo-endorphin, a new hypothalamic "big" Leu-enkephalin of porcine origin: its purification and the complete amino acid sequence. Biochem Biophys Res Commun. 1981 Apr 15;99(3):864-70. DOI:10.1016/0006-291x(81)91243-2
[2] Yang DJ, et al. β-Neoendorphin Enhances Wound Healing by Promoting Cell Migration in Keratinocyte. Molecules. 2020 Oct 12;25(20):4640. DOI:10.3390/molecules25204640

Beta-Neoendorphin Preparation Products And Raw materials

Raw materials

Preparation Products

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77739-21-0, Beta-NeoendorphinRelated Search:

BETA-ENDORPHIN (CAMEL) H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Val-His-Lys-Lys-Gly-Gln-OH β-Interleukin II (44-56) BETA-ENDORPHIN (EQUINE) B-ENDORPHIN (HUMAN) (B-LIPOTROPIN 61-91, b-Endorphin (6-31), human BETA-LIPOTROPIN (1-10) (PORCINE) β-catenin peptide H-TYR-PRO-PHE-VAL-GLU-PRO-ILE-OH BETA-ENDORPHIN HUMAN SYNTHETIC BETA-LIPOTROPIN (61-69) H-TYR-GLY-GLY-PHE-OH LYS-LYS-GLY-GLU BETA-ENDORPHIN (RAT) H-ALA-PHE-PRO-OH GLY-TYR-ALA PHE-PRO H-ALA-ALA-TYR-ALA-OH

  • BETA-NEOENDORPHIN
  • BETA-NEO-ENDORPHIN (PORCINE)
  • H-TYR-GLY-GLY-PHE-LEU-ARG-LYS-TYR-PRO-OH
  • PRODYNORPHIN (175-183) (HUMAN, PORCINE)
  • TYR-GLY-GLY-PHE-LEU-ARG-LYS-TYR-PRO
  • B-neoendorphin
  • L-Tyr-Gly-Gly-L-Phe-L-Leu-L-Arg-L-Lys-L-Tyr-L-Pro-OH
  • TYR-GLY-GLY-PHE-LEU-ARG-LYS-TYR-PRO: YGGFLRKYP
  • β-Neoendorphin, Prodynorphin (175-183) (human, porcine)
  • L-Proline, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-L-arginyl-L-lysyl-L-tyrosyl-
  • β-Neo-Endorphin (Porcine)
  • β-Neo-Endorphin
  • β-Neoendorphin (human)
  • ((S)-2-((S)-2-((S)-2-(2-(2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)acetamido)acetamido)-3-phenylpropanamido)-4-methylpentanamido)-5-((diaminomethylene)amino)pentanoyl)-L-lysyl-L-tyrosyl-L-proline
  • b-Neoendorphin (human) (9CI)
  • sh-Nonapeptide-3
  • β-Neo-Endorphin (Porcine) (0.5 mg vial)
  • 77739-21-0
  • C54H77N13O12