ChemicalBook > CAS DataBase List > 1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER

1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER

Product Name
1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
CAS No.
111247-60-0
Chemical Name
1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
Synonyms
BUTTPARK 90\06-42;ETHYL1-PYRIMIDIN-2-YLPIPERIDINE-4-CARBOXYLATE;Ethyl 1-pyrimidin-2-ylpiperidine-4-carboxylate 95+%;1-(2-pyrimidinyl)-4-piperidinecarboxylic acid ethyl ester;1-Pyrimidin-2-yl-piperidine-4-carboxylicacidethylester95%;1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER;4-Piperidinecarboxylic acid, 1-(2-pyriMidinyl)-, ethyl ester;1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 95%;1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH
CBNumber
CB0772826
Molecular Formula
C12H17N3O2
Formula Weight
235.28
MOL File
111247-60-0.mol
More
Less

1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER Property

Boiling point:
373.4±52.0 °C(Predicted)
Density 
1.163±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
5.04±0.33(Predicted)
More
Less

Safety

HS Code 
2933599590
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

TRC
Product number
E937093
Product name
Ethyl1-Pyrimidin-2-yl-piperidine-4-carboxylate
Packaging
10mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
083555
Product name
Ethyl 1-pyrimidin-2-ylpiperidine-4-carboxylate
Purity
97%
Packaging
1g
Price
$166
Updated
2021/12/16
Apolloscientific
Product number
OR111002
Product name
Ethyl 1-pyrimidin-2-ylpiperidine-4-carboxylate
Purity
95+%
Packaging
5g
Price
$181
Updated
2021/12/16
SynQuest Laboratories
Product number
4H58-1-HX
Product name
Ethyl 1-pyrimidin-2-ylpiperidine-4-carboxylate
Packaging
10g
Price
$348
Updated
2021/12/16
AK Scientific
Product number
Z3888
Product name
Ethyl1-pyrimidin-2-yl-piperidine-4-carboxylate
Packaging
10g
Price
$361
Updated
2021/12/16
More
Less

1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Synthesis

1722-12-9

1126-09-6

111247-60-0

2-Chloropyrimidine (2.28 g, 20 mmol) and ethyl 4-piperidinecarboxylate (4.72 g, 30 mmol) were mixed in toluene (10 mL) and heated to reflux for 18 hours. After completion of the reaction, the mixture was cooled to room temperature, diluted with ethyl acetate and washed with saturated aqueous sodium bicarbonate. The organic layer was separated, dried and the solvent was removed under vacuum. The residue was purified by rapid chromatography on silica gel (eluent: ethyl acetate/petroleum ether, 40/60, v/v) to afford ethyl 1-(2-pyrimidinyl)piperidine-4-carboxylate as a colorless oil in a yield of 4.00 g in 81%. Mass spectrum (ESI+): [M + H]+ = 236.0.

References

[1] Farmaco, 1993, vol. 48, # 10, p. 1439 - 1445
[2] Patent: WO2010/97576, 2010, A1. Location in patent: Page/Page column 39
[3] Journal of Medicinal Chemistry, 2013, vol. 56, # 21, p. 8696 - 8711

1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER Suppliers

Belgium 1 China 28 France 1 Germany 2 India 1 United Kingdom 6 United States 14 Global 53
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Shanghai ChuangYan Chemical Technology Co., Ltd.
Tel
021-11111111 11111111111
Fax
qq:546919421
Email
546919421@qq.com
Country
China
ProdList
3522
Advantage
55
Fuyang JSK Biomedical Technology Co., Ltd
Tel
18915409046
Fax
0510-86566870
Email
1102409417@qq.com
Country
China
ProdList
268
Advantage
55
Changzhou Hopschain Chemical Co.,Ltd.
Tel
0519-85528066 13775048983
Fax
0519-85528066
Email
sales@hopschem.com
Country
China
ProdList
31553
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Taian Jiaye Biotechnology Co.Ltd
Tel
13127280945
Email
285424065@qq.com
Country
China
ProdList
9976
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
More
Less

View Lastest Price from 1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 111247-60-0
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-07

111247-60-0, 1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTERRelated Search:

1-(2-Pyrimidinyl)piperidine-4-carboxylic acid 1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-(2-PYRIMIDINYL)PIPERIDINE-4-METHANOL ETHYL 1-[4-(TRIFLUOROMETHYL)PYRIMIDIN-2-YL]PIPERIDINE-4-CARBOXYLATE 1-(4-METHYL-6-TRIFLUOROMETHYL-PYRIMIDIN-2-YL)-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-[6-(2-ETHOXYCARBONYL-ACETYL)-2-METHYL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL]-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-[6-(3-CYANO-PHENYLCARBAMOYL)-2-METHYL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL]-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-[6-(3-CYANO-BENZENESULFONYL)-2-METHYL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL]-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-[6-(3-METHOXY-BENZENESULFONYL)-2-METHYL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL]-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-(2-PHENYL-6-PYRIDIN-3-YLMETHYL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL)-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-[6-(3-CYANO-BENZYL)-2-PHENYL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL]-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-[6-(3-CYANO-BENZENESULFONYL)-2-PHENYL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL]-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-(2-METHYL-6-PYRIDIN-3-YLMETHYL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL)-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-(3-FORMYL-4-OXO-4H-PYRIDO[1,2-A]PYRIMIDIN-2-YL)-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-(6-ACETYL-2-METHYL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL)-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-[2-METHYL-6-(THIOPHENE-2-CARBONYL)-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL]-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-[6-(3-CYANO-BENZYL)-2-PYRIDIN-2-YL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL]-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 1-[6-(3-CYANO-BENZOYL)-2-METHYL-5,6,7,8-TETRAHYDRO-PYRIDO[4,3-D]PYRIMIDIN-4-YL]-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER

  • 4-Piperidinecarboxylic acid, 1-(2-pyriMidinyl)-, ethyl ester
  • 1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER
  • BUTTPARK 90\06-42
  • 1-Pyrimidin-2-yl-piperidine-4-carboxylicacidethylester95%
  • ETHYL1-PYRIMIDIN-2-YLPIPERIDINE-4-CARBOXYLATE
  • 1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER 95%
  • 1-(2-pyrimidinyl)-4-piperidinecarboxylic acid ethyl ester
  • Ethyl 1-pyrimidin-2-ylpiperidine-4-carboxylate 95+%
  • 1-PYRIMIDIN-2-YL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH
  • 111247-60-0
  • Pyrans, Piperidines & Piperazines
  • Esters
  • Pyrans, Piperidines &Piperazines