20-HETE-D6

Product Name: 20-HETE-D6
CAS No.: 2548939-89-3
Chemical Name: 20-HETE-D6
Synonyms: 20-HETE-D6;20-HYDROXY-5Z,8Z,11Z,14Z-EICOSATETRAENOIC-16,16,17,17,18,18-D6 ACID
CBNumber: CB0777083
Molecular Formula: C20H32O3
Formula Weight: 320.47
MOL File: Mol file

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20-HETE-D6 Property

solubility: DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 500 μg/ml
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 390030
Product name: 20-HETE-d6
Purity: ≥99% deuterated forms (d1-d6)
Packaging: 25μg
Price: $182
Updated: 2024/03/01

Cayman Chemical

Product number: 390030
Product name: 20-HETE-d6
Purity: ≥99% deuterated forms (d1-d6)
Packaging: 50μg
Price: $343
Updated: 2024/03/01

Cayman Chemical

Product number: 24923
Product name: 20-HETE-d6 MaxSpec® Standard
Purity: ≥95%
Packaging: 10 μg
Price: $249
Updated: 2024/03/01

Cayman Chemical

Product number: 390030
Product name: 20-HETE-d6
Purity: ≥99% deuterated forms (d1-d6)
Packaging: 100μg
Price: $647
Updated: 2024/03/01

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20-HETE-D6 Chemical Properties,Usage,Production

Description

20-HETE-d₆ contains six deuterium atoms at the 16, 16', 17, 17', 18 and 18' positions. It is intended for use as an internal standard for the quantification of 20-HETE by GC- or LC-MS. 20-HETE is a cytochrome P450 (CYP450) metabolite postulated to play an autacoid role in the renal and cerebral vasculature.¹ In rat cerebral microvessels, 20-HETE is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction.² 20-HETE is excreted mainly as the glucuronide conjugate. The concentration of free 20-HETE (20-40 pg/ml in human urine) is about 10-fold lower than the corresponding concentration of the 20-glucuronide.³

References

1. McGiff, J.C., and Quilley, J. 20-HETE and the kidney: Resolution of old problems and new beginnings Am. J. Physiol. 277(3),R607-R623(1999).
2. Gebremedhin, D., Lange, A.R., Lowry, T.F., et al. Production of 20-HETE and its role in autoregulation of cerebral blood flow Circ. Res. 87(1),60-65(2000).
3. Prakash, C., Zhang, J.Y., Falck, J.R., et al. 20-Hydroxyeicosatetraenoic acid is excreted as a glucuronide conjugate in human urine Biochem. Biophys. Res. Commun. 185(2),728-733(1992).

20-HETE-D6 Preparation Products And Raw materials

Raw materials

Preparation Products

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20-HETE-D6 Suppliers

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2548939-89-3, 20-HETE-D6Related Search:

20-HETE

20-HETE-D6

20-HYDROXY-5Z,8Z,11Z,14Z-EICOSATETRAENOIC-16,16,17,17,18,18-D6 ACID

2548939-89-3