1-PYRIDIN-4-YLPIPERIDIN-4-ONE

Product Name: 1-PYRIDIN-4-YLPIPERIDIN-4-ONE
CAS No.: 126832-81-3
Chemical Name: 1-PYRIDIN-4-YLPIPERIDIN-4-ONE
Synonyms: 1-pyridin-4-yl-4-piperidinone;1-PYRIDIN-4-YLPIPERIDIN-4-ONE;1-(4-Pyridinyl)-4-piperidinone;4-Piperidinone, 1-(4-pyridinyl)-;2,3,5,6-TETRAHYDRO-[1,4']BIPYRIDINYL-4-ONE
CBNumber: CB0795898
Molecular Formula: C10H12N2O
Formula Weight: 176.22
MOL File: 126832-81-3.mol

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1-PYRIDIN-4-YLPIPERIDIN-4-ONE Property

Boiling point:: 340.8±32.0 °C(Predicted)
Density: 1.163±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Room Temperature
pka: 10.54±0.10(Predicted)

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

TRC

Product number: P995728
Product name: 1-Pyridin-4-ylpiperidin-4-one
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 074693
Product name: 1-Pyridin-4-ylpiperidin-4-one
Purity: 95+%
Packaging: 250mg
Price: $231
Updated: 2021/12/16

Apolloscientific

Product number: OR907054
Product name: 1-Pyridin-4-ylpiperidin-4-one
Purity: 95%
Packaging: 1g
Price: $327
Updated: 2021/12/16

AK Scientific

Product number: X9679
Product name: 1-Pyridin-4-ylpiperidin-4-one
Packaging: 5g
Price: $342
Updated: 2021/12/16

AK Scientific

Product number: X9679
Product name: 1-Pyridin-4-ylpiperidin-4-one
Packaging: 10g
Price: $483
Updated: 2021/12/16

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1-PYRIDIN-4-YLPIPERIDIN-4-ONE Chemical Properties,Usage,Production

Synthesis

166954-75-2

126832-81-3

The general procedure for the synthesis of 1-(4-pyridyl)-piperidin-4-one from the compound (CAS:166954-75-2) was as follows: 79.7 g of the aforementioned ketone was dissolved in 2 L of tetrahydrofuran, followed by the addition of 1000 mL of 6 N hydrochloric acid solution. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the solvent was removed by evaporation and concentration, and the pH was adjusted to alkaline with semi-concentrated ammonia. Extraction was carried out using dichloromethane and the combined organic phases were concentrated by evaporation to give 64.2 g (quantitative yield) of 2,3,5,6-tetrahydro-[1,4']bipyridin-4-one, which has a melting point of 102 °C.

References

[1] Patent: US2003/236266, 2003, A1. Location in patent: Page 7
[2] European Journal of Medicinal Chemistry, 2017, vol. 139, p. 128 - 152
[3] Patent: WO2010/81851, 2010, A1. Location in patent: Page/Page column 17
[4] Patent: US2012/71461, 2012, A1. Location in patent: Page/Page column 147
[5] Tetrahedron Letters, 2007, vol. 48, # 14, p. 2519 - 2525

1-PYRIDIN-4-YLPIPERIDIN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-PYRIDIN-4-YLPIPERIDIN-4-ONE Suppliers

China 35 India 1 Ukraine 1 United Kingdom 1 United States 11 Global 49

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126832-81-3, 1-PYRIDIN-4-YLPIPERIDIN-4-ONERelated Search:

Pyridinethione 4-HYDROXYPYRIDINE 4-Piperidinone 1-pyridin-2-ylpiperidin-4-one 1-pyridin-3-ylpiperidin-4-one 1-pyridin-4-ylpiperidin-4-one oxime 1-pyridin-2-ylpiperidin-4-one oxime 1-PYRIDIN-4-YLPIPERIDIN-4-ONE 1-(7-chloroquinolin-4-yl)piperidin-4-one

1-PYRIDIN-4-YLPIPERIDIN-4-ONE

1-pyridin-4-yl-4-piperidinone

2,3,5,6-TETRAHYDRO-[1,4']BIPYRIDINYL-4-ONE

1-(4-Pyridinyl)-4-piperidinone

4-Piperidinone, 1-(4-pyridinyl)-

126832-81-3