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Bromoacetamido-PEG5-DOTA

Product Name
Bromoacetamido-PEG5-DOTA
CAS No.
2353410-19-0
Chemical Name
Bromoacetamido-PEG5-DOTA
Synonyms
Bromoacetamido-PEG5-DOTA;1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic acid, 10-(23-bromo-2,22-dioxo-6,9,12,15,18-pentaoxa-3,21-diazatricos-1-yl)-
CBNumber
CB08054689
Molecular Formula
C30H55BrN6O13
Formula Weight
787.69
MOL File
2353410-19-0.mol
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Bromoacetamido-PEG5-DOTA Property

Boiling point:
976.6±65.0 °C(Predicted)
Density 
1.314±0.06 g/cm3(Predicted)
pka
1.83±0.10(Predicted)
form 
Oil
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-24089
Product name
Bromoacetamido-PEG5-DOTA
Purity
98%
Packaging
1mg
Price
$350
Updated
2021/12/16
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Bromoacetamido-PEG5-DOTA Chemical Properties,Usage,Production

Description

Bromoacetamido-PEG3-DOTA is a PEG linker containing a bromine moiety and a t-butyl protecting group. The hydrophilic PEG spacer increases the water solubility of a compound in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The DOTA group can be ionized and is susceptible for chelating di- and trivalent cations.

Uses

Bromoacetamido-PEG5-DOTA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Bromoacetamido-PEG5-DOTA Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromoacetamido-PEG5-DOTA Suppliers

Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
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32435
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58
Shanghai Haohong Pharmaceutical Co., Ltd.
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400-8210725 4008210725
Email
malulu@leyan.com
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China
ProdList
55000
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58
Zhengzhou Akem Chemical Co., Ltd
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13303867194
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3001317055@qq.com
Country
China
ProdList
9681
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58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
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China
ProdList
29757
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58
Affinity(Wuhan)Ltd.
Tel
15841022315
Email
sales@affinitytech.cn
Country
China
ProdList
3000
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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0431-80514535 19917294565
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et@chemextension.com
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China
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5061
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Shanghai Easy CDMO Co.,Ltd
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021-61734564 13854185395;
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info@easycdmo.com
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China
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10024
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Jilin Chinese Academy of Sciences-yanshen Technology
Tel
18143011203
Email
ET-market@chemextension.com
Country
China
ProdList
32034
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58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29496
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58
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View Lastest Price from Bromoacetamido-PEG5-DOTA manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Bromoacetamido-PEG5-DOTA 2353410-19-0
Price
US $0.00/mg
Min. Order
250mg
Purity
>95.00%
Supply Ability
250mg
Release date
2024-05-11