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Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-

Product Name
Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-
CAS No.
2254541-79-0
Chemical Name
Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-
Synonyms
4,4'-((2,2'-bis(hydroxymethyl)-[1,1'-biphenyl]-4,4'-diyl)bis(oxy))dibenzonitrile;Crisaborole Diamer;Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-;4-((2,2'-bis(hydroxymethyl)-4'-(4-isocyanophenoxy)-[1,1'-biphenyl]-4-yl)oxy)benzonitrile;Crisaborole Dimer ImpurityQ: What is Crisaborole Dimer Impurity Q: What is the CAS Number of Crisaborole Dimer Impurity
CBNumber
CB08095082
Molecular Formula
C28H20N2O4
Formula Weight
448.47
MOL File
2254541-79-0.mol
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Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Property

Boiling point:
702.3±60.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
pka
13.95±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Chemical Properties,Usage,Production

Uses

Crisaborole Diamer Impurity is an impurity of Crisaborole (H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-(4-Cyanophenoxy)-2,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.

Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Suppliers

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2254541-79-0, Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-Related Search:


  • Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-
  • 4-((2,2'-bis(hydroxymethyl)-4'-(4-isocyanophenoxy)-[1,1'-biphenyl]-4-yl)oxy)benzonitrile
  • Crisaborole Diamer
  • 4,4'-((2,2'-bis(hydroxymethyl)-[1,1'-biphenyl]-4,4'-diyl)bis(oxy))dibenzonitrile
  • Crisaborole Dimer ImpurityQ: What is Crisaborole Dimer Impurity Q: What is the CAS Number of Crisaborole Dimer Impurity
  • 2254541-79-0