ChemicalBook > CAS DataBase List > Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-
Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-
- Product Name
- Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-
- CAS No.
- 2254541-79-0
- Chemical Name
- Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-
- Synonyms
- 4,4'-((2,2'-bis(hydroxymethyl)-[1,1'-biphenyl]-4,4'-diyl)bis(oxy))dibenzonitrile;Crisaborole Diamer;Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-;Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-;4-((2,2'-bis(hydroxymethyl)-4'-(4-isocyanophenoxy)-[1,1'-biphenyl]-4-yl)oxy)benzonitrile;Crisaborole Dimer ImpurityQ: What is Crisaborole Dimer Impurity Q: What is the CAS Number of Crisaborole Dimer Impurity
- CBNumber
- CB08095082
- Molecular Formula
- C28H20N2O4
- Formula Weight
- 448.47
- MOL File
- 2254541-79-0.mol
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Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Property
- Boiling point:
- 702.3±60.0 °C(Predicted)
- Density
- 1.37±0.1 g/cm3(Predicted)
- pka
- 13.95±0.10(Predicted)
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Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Chemical Properties,Usage,Production
Uses
Crisaborole Diamer Impurity is an impurity of Crisaborole (H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.
Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Preparation Products And Raw materials
Raw materials
Preparation Products
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