[1,1'-Biphenyl]-2,2',5,5'-tetrol, 4,4'-dimethyl-
- Product Name
- [1,1'-Biphenyl]-2,2',5,5'-tetrol, 4,4'-dimethyl-
- CAS No.
- 4371-34-0
- Chemical Name
- [1,1'-Biphenyl]-2,2',5,5'-tetrol, 4,4'-dimethyl-
- Synonyms
- NSC 2805;NSC2805, 10 mM in DMSO;4,4'-dimethylbiphenyl-2,2',5,5'-tetr;4,4'-dimethylbiphenyl-2,2',5,5'-tetrol;4,4'-Dimethyl-[1,1'-biphenyl]-2,2',5,5'-tetraol;[1,1'-Biphenyl]-2,2',5,5'-tetrol, 4,4'-dimethyl-;[1,1'-Biphenyl]-2,2',5,5'-tetrol, 4,4'-dimethyl-;2-(2,5-Dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol
- CBNumber
- CB08178172
- Molecular Formula
- C14H14O4
- Formula Weight
- 246.26
- MOL File
- 4371-34-0.mol
[1,1'-Biphenyl]-2,2',5,5'-tetrol, 4,4'-dimethyl- Property
- Melting point:
- 170-172 °C(Solv: ethanol (64-17-5))
- Boiling point:
- 501.6±50.0 °C(Predicted)
- Density
- 1.360±0.06 g/cm3(Predicted)
- storage temp.
- 4°C, stored under nitrogen
- form
- Solid
- pka
- 9.92±0.50(Predicted)
- color
- Pale purple to gray
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
[1,1'-Biphenyl]-2,2',5,5'-tetrol, 4,4'-dimethyl- Chemical Properties,Usage,Production
Description
NSC-2805 is a WWP2 ubiquitin ligase inhibitor.
Uses
NSC2805 is a WWP2 ubiquitin ligase inhibitor that can significant inhibit WWP2 activity with an IC50 of 0.38 μM. NSC2805 can be used for the research of cancer[1].
References
[1] Jessica E Watt, et al. Discovery of Small Molecule WWP2 Ubiquitin Ligase Inhibitors. Chemistry. 2018 Dec 3;24(67):17677-17680. DOI:10.1002/chem.201804169
[1,1'-Biphenyl]-2,2',5,5'-tetrol, 4,4'-dimethyl- Preparation Products And Raw materials
Raw materials
Preparation Products
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