BRUSATOL

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Physical Form Description

Product Name: BRUSATOL
CAS No.: 114420-67-6
Chemical Name: BRUSATOL
Synonyms: BRUSATOL;Regaloside B;b-D-Glucopyranoside,2-(acetyloxy)-1-[[[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]oxy]methyl]ethyl,[S-(E)]-;β-D-Glucopyranoside, (1S)-2-(acetyloxy)-1-[[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]methyl]ethyl
CBNumber: CB0823115
Molecular Formula: C20H26O11
Formula Weight: 442.41
MOL File: 114420-67-6.mol

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BRUSATOL Property

Boiling point:: 727.5±60.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
form: Solid
pka: 8.58±0.15(Predicted)
color: White to off-white
CAS DataBase Reference: 114420-67-6

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0135214
Product name: RegalosideB
Packaging: 1mg
Price: $200
Updated: 2021/12/16

Arctom

Product number: CFN91844
Product name: RegalosideB
Purity: ≥98%
Packaging: 10mg
Price: $218
Updated: 2021/12/16

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BRUSATOL Chemical Properties,Usage,Production

Physical Form

Powder

Description

Brusatol is a natural quassinoid that shows a potential therapeutic use in cancer models by the inhibition of Nuclear factor erythroid 2-related factor 2 (Nrf2) and is capable of inducing a variety of biological effects. The effects of Brusatol on oocyte meiosis has not been addressed.

Uses

Clinically, the research shows brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism, and it provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity. Brusatol overcomes chemoresistance through inhibition of protein translation.

BRUSATOL Preparation Products And Raw materials

Raw materials

Preparation Products

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BRUSATOL

Regaloside B

β-D-Glucopyranoside, (1S)-2-(acetyloxy)-1-[[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]methyl]ethyl

b-D-Glucopyranoside,2-(acetyloxy)-1-[[[3-(4-hydroxyphenyl)-1-oxo-2-propenyl]oxy]methyl]ethyl,[S-(E)]-

114420-67-6

14907-98-7

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C26H32O11