4-METHYL-3-[(1-METHYL-4-NITRO-1H-IMIDAZOL-5-YL)THIO]-4H-1,2,4-TRIAZOLE Property

Boiling point:

553.7±60.0 °C(Predicted)

Density 

1.68±0.1 g/cm3(Predicted)

storage temp. 

Store at +4°C

form 

Solid

pka

0.67±0.10(Predicted)

color 

Light yellow to orange

Water Solubility 

<2.4mg/ml in Water

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

4-METHYL-3-[(1-METHYL-4-NITRO-1H-IMIDAZOL-5-YL)THIO]-4H-1,2,4-TRIAZOLE Chemical Properties,Usage,Production

Uses

MNITMT is a novel, non-toxic immunosuppressive agent.

Definition

ChEBI: 4-methyl-3-[(3-methyl-5-nitro-4-imidazolyl)thio]-1,2,4-triazole is an aryl sulfide.

Biological Activity

Novel, non-toxic immunosuppressive agent. Inhibits human mixed lymphocyte reaction in vitro (ED 50 = 2.7 μ M) and prolongs skin graft survival in mice. Produces a 98.1% reduction in antibody response following oral administration in rabbits.