ChemicalBook > CAS DataBase List > Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-
Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-
- Product Name
- Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-
- CAS No.
- 57935-66-7
- Chemical Name
- Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-
- Synonyms
- NicergolineImpurity2;10-Hydroxynicergoline;10α-Hydroxy Nicergoline;Nicergoline EP Impurity 7;Ergoline-8-methanol Indolo[4,3-fg]quinoline Derivative;Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)-
- CBNumber
- CB08366638
- Molecular Formula
- C23H24BrN3O3
- Formula Weight
- 470.37
- MOL File
- 57935-66-7.mol
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Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)- Property
- Boiling point:
- 621.7±55.0 °C(Predicted)
- Density
- 1.54±0.1 g/cm3(Predicted)
- pka
- 13.80±0.40(Predicted)
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Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)- Chemical Properties,Usage,Production
Uses
10α-Hydroxy Nicergoline is an impurity of Nicergoline (N394550) which is a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia. Nicergoline has shown to protect cultured neurons against β-amyloid toxicity. Nicergoline protects against neuronal cell death induced by activated microglia and astrocytes through the inhibition of inflammatory mediators and the upregulation of neurotrophic factors by glial cells. Nicergoline is a drug used for age-dependent cognitive impairment and it protects cultured neurons against β-amyloid toxicity.
Ergoline-8-methanol, 10-hydroxy-1,6-dimethyl-, 8-(5-bromo-3-pyridinecarboxylate), (8β)- Preparation Products And Raw materials
Raw materials
Preparation Products
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