ChemicalBook > CAS DataBase List > 6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE

6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE

Product Name
6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE
CAS No.
4720-83-6
Chemical Name
6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE
Synonyms
NSC 657815;6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE;cis-6-Oxa-bicyclo3.2.1oct-3-en-7-one
CBNumber
CB0842725
Molecular Formula
C7H8O2
Formula Weight
124.14
MOL File
4720-83-6.mol
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6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE Property

Boiling point:
263.1±29.0 °C(Predicted)
Density 
1.196±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
Appearance
Colorless to light yellow Liquid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
E590118
Product name
6-Oxabicyclo[3.2.1]oct-3-en-7-one
Packaging
500mg
Price
$795
Updated
2021/12/16
J&W Pharmlab
Product number
05R0973
Product name
6-Oxa-bicyclo[3.2.1]oct-3-en-7-one
Purity
96%
Packaging
100mg
Price
$137
Updated
2021/12/16
Chemenu
Product number
CM123048
Product name
6-oxabicyclo[3.2.1]oct-3-en-7-one
Purity
95%
Packaging
1g
Price
$355
Updated
2021/12/16
Crysdot
Product number
CD11120671
Product name
6-Oxabicyclo[3.2.1]oct-3-en-7-one
Purity
95+%
Packaging
1g
Price
$376
Updated
2021/12/16
Alichem
Product number
4720836
Product name
6-Oxabicyclo[3.2.1]oct-3-en-7-one
Packaging
1g
Price
$410.4
Updated
2021/12/16
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6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE Chemical Properties,Usage,Production

Uses

6-Oxabicyclo[3.2.1]oct-3-en-7-one is used in the convergent total synthesis of Leustroducsin B.

Synthesis

76140-13-1

4720-83-6

General procedure for the synthesis of 6-oxabicyclo[3.2.1]oct-3-en-7-one from 4-iodo-3-cyclohexanecarboxylic acid lactone: to a solution of 4-iodo-6-oxabicyclo[3.2.1]octan-1-one (8.00 g, 31.7 mmol) in benzene (100 ml), 1,8-diazabicyclo[5.4.0]undec-7-ene (7.9 g, 32 mmol). The mixture was heated to reflux for 6 hours under nitrogen protection. After completion of the reaction, the reaction solution was cooled, the white precipitate was collected by filtration and washed with ether (100 ml). The filtrates were combined and washed sequentially with water (50 ml), 1N HCl (50 ml) and brine (25 ml) and then dried with magnesium sulfate. The solvent was removed by rotary evaporation to afford the target product olefin as a light brown oil (2.6 g, 66% yield).

References

[1] Patent: WO2005/37832, 2005, A2. Location in patent: Page/Page column 67
[2] Journal of the American Chemical Society, 2010, vol. 132, # 35, p. 12179 - 12181
[3] Patent: WO2014/70991, 2014, A2. Location in patent: Page/Page column 68
[4] Patent: WO2015/48616, 2015, A1. Location in patent: Paragraph 00128

6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE Suppliers

China 17 United States 6 Global 23
Tetranov Biopharm
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China
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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Shanghai Fluoking Chemicals Co., Ltd.
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Fuxin Pharmaceutical
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4720-83-6, 6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONERelated Search:

6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE

  • 6-OXABICYCLO[3.2.1]OCT-3-EN-7-ONE
  • cis-6-Oxa-bicyclo3.2.1oct-3-en-7-one
  • NSC 657815
  • 4720-83-6