4-(Methylamino)phenol Property

Melting point:

87 °C

Boiling point:

262.7±23.0 °C(Predicted)

Density 

1.147±0.06 g/cm3(Predicted)

pka

11.31±0.26(Predicted)

CAS DataBase Reference

150-75-4

EPA Substance Registry System

4-(Methylamino)phenol (150-75-4)

Safety

RIDADR 

3077

HazardClass 

9

PackingGroup 

III

Hazardous Substances Data

150-75-4 (Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H332Harmful if inhaled

H341Suspected of causing genetic defects

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

4-(Methylamino)phenol Chemical Properties,Usage,Production

Description

4-(Methylamino)phenol is an important organic reagent, with a wide range of pathways, can be used as a reaction reagent for oxidative coupling reaction, analytical detection reagent, photographic developer, corrosion inhibitor for steel in chlorate solution, hair dye developer and so on.

Uses

4-Hydroxy-N-methylaniline is a useful synthetic intermediate. It is used to synthesize arylidene amino azolones with anticancer activity. It is also used to prepare N-(4-hydroxyphenyl)retinamide analogs with antitumor and apoptosis-inducing activities.

Definition

ChEBI: 4-methylaminophenol is the phenol that is the N-methyl derivative of 4-aminophenol. It has a role as an allergen. It is functionally related to a 4-aminophenol.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 43, p. 766, 1995 DOI: 10.1248/cpb.43.766

Contact allergens

Metol is contained in black and white film developers and caused contact dermatitis in photographers.