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propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate

Product Name
propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate
CAS No.
1421-14-3
Chemical Name
propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate
Synonyms
Epontol;WH-5668;TH-2180;FBA-1420;BAY-1420;Fabantol;Fabontal;Sombrevin;propanidid;Bayer-1420
CBNumber
CB0875008
Molecular Formula
C18H27NO5
Formula Weight
337.41
MOL File
1421-14-3.mol
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propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Property

Boiling point:
bp0.7 210-212°
Density 
1.2043 (rough estimate)
refractive index 
1.5000 (estimate)
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Ethyl Acetate (Slightly)
form 
Oil
color 
Pale Yellow to Yellow
EPA Substance Registry System
Propanidid (1421-14-3)
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Safety

Toxicity
LD50 orally in rats: >10,000 mg/kg (Goldenthal)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
S676765
Product name
Sombrevin
Packaging
25mg
Price
$85
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0015482
Product name
PROPANIDID
Purity
95.00%
Packaging
5MG
Price
$502.28
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
61759
Product name
Sombrevin
Packaging
5G
Price
$2200
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0015482
Product name
PROPANIDID
Purity
95.00%
Packaging
25G
Price
$5649
Updated
2021/12/16
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propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Chemical Properties,Usage,Production

Chemical Properties

yellow oil bp0.7 210-212°C soluble in alcohol, chloroform, essentially water insoluble anasthetic Epontol (Bayer) Sombrevin

Uses

Anesthetic (intravenous).

Uses

Sombrevin, is an ultra short-acting phenylacetate general anesthetic.

Definition

ChEBI: Propanidid is a member of methoxybenzenes.

brand name

Epontol (Farbenfabriken Bayer A.G., Germany).

Clinical Use

Propanidid is used as a very short- to shortacting intravenous anesthetic for minor surgery and gynecology. It is characterized by rapid onset of and quick recovery from anesthesia, producing surgical anesthesia for 3 – 4 min. Repeated injections can be used to prolong the anesthesia. Postanesthetic sleep does not occur because the propyl ester is hydrolyzed rapidly in the patient to form inactive 3-methoxy-4- (N,N-diethylcarbamoylmethoxy)phenylacetic acid. After 20 – 30 min the patients generally are completely responsive .

Synthesis

Propanidid , propyl 3- methoxy-4-(N,N-diethylcarbamoylmethoxy)- phenylacetate, is a colorless to pale yellowish water-insoluble oil. It is prepared from the propyl ester of sodium homovanillic acid and N,N-diethylchloroacetamide .

propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57412
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30240
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Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
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58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
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TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
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Suzhou Zhixin Biotechnology Co., Ltd.
Tel
0512-65118909 15162312715
Email
sales@szzxbio.com
Country
China
ProdList
3004
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Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
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China
ProdList
11974
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Shanghai Bolu Biotechnology Co., Ltd
Tel
13062875887 13062875887
Email
3662942976@QQ.com
Country
China
ProdList
436
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1421-14-3, propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetateRelated Search:


  • KEJXLQUPYHWCNM-UHFFFAOYSA-N
  • propanidid
  • propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate
  • PROPANIDIDE
  • Bayer-1420
  • Epontol
  • FBA-1420
  • Sombrevin
  • TH-2180
  • WH-5668
  • 2-[4-[2-(diethylamino)-2-keto-ethoxy]-3-methoxy-phenyl]acetic acid propyl ester
  • propyl 2-[4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl]acetate
  • propyl 2-[4-[2-(diethylamino)-2-oxo-ethoxy]-3-methoxy-phenyl]ethanoate
  • Benzeneacetic acid, 4-[2-(diethylamino)-2-oxoethoxy]-3-methoxy-, propyl ester
  • propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate USP/EP/BP
  • BAY-1420
  • Fabantol
  • Fabontal
  • BAY-1420, Sombrevin
  • propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate/Sombrevin
  • 1421-14-3