Etozolin
- Product Name
- Etozolin
- CAS No.
- 73-09-6
- Chemical Name
- Etozolin
- Synonyms
- GO-687;GO 687;Elkapin;W-2900A;Etozolin;Etozoline;[3-Methyl-4-oxo-5-(1-piperidinyl)thiazolidin-2-ylidene]acetic acid ethyl;[3-Methyl-4-oxo-5-(1-piperidinyl)thiazolidin-2-ylidene]acetic acid ethyl ester;Acetic acid, 2-[3-methyl-4-oxo-5-(1-piperidinyl)-2-thiazolidinylidene]-, ethyl ester
- CBNumber
- CB0875664
- Molecular Formula
- C13H20N2O3S
- Formula Weight
- 284.378
- MOL File
- 73-09-6.mol
Etozolin Property
- Melting point:
- 140°
- Boiling point:
- 230.9°C (rough estimate)
- Density
- 1.2117 (rough estimate)
- refractive index
- 1.6360 (estimate)
- pka
- 4.11±0.20(Predicted)
Safety
- Toxicity
- LD50 in male mice, rats (mg/kg): 1210, 1575 i.p.; in male, female mice, rats (mg/kg): 8670, 9360, 11040, 10250 orally (Herrmann)
N-Bromosuccinimide Price
- Product number
- API0011380
- Product name
- ETHYL (2Z)-[3-METHYL-4-OXO-5-(1-PIPERIDINYL)-1,3-THIAZOLIDIN-2-YLIDENE]ETHANOATE
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $505.73
- Updated
- 2021/12/16
- Product number
- API0011380
- Product name
- ETHYL (2Z)-[3-METHYL-4-OXO-5-(1-PIPERIDINYL)-1,3-THIAZOLIDIN-2-YLIDENE]ETHANOATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $1250
- Updated
- 2021/12/16
Etozolin Chemical Properties,Usage,Production
Originator
Elkapin,Goedecke,W. Germany,1977
Uses
Diuretic.
Manufacturing Process
To a stirred solution of 20 g (0.1 mol) 2-carbethoxymethylene-3-methyl-4-
thiazolidinone in 120 ml chloroform is added, dropwise, a solution of 5 ml (0.1
mol) bromine in 20 ml chloroform. The solvent is removed by distillation and
the residue crystallized from methanol to yield 18 g (65%) of 2-
carbethoxymethylen-3-methyl-5-bromo-4-thiazolidinone, MP 76°C.
To a solution of 28 g (0.1 mol) 2-carbethoxymethylene-3-methyl-5-bromo-4-
thiazolidinone prepared as described in 200 ml benzene is added (0.2 mol)
piperidine and the mixture is allowed to stand for 3 hours at 25°C. The
resulting suspension is filtered to remove the precipitated piperidine
hydrobromide and the filtrate is evaporated to dryness. The residue is taken
up in ether, filtered and the filtrate saturated with dry hydrogen chloride to
yield the hydrochloride salt of 2-carbethoxymethylene-3-methyl-5-piperidino-
4-thiazolidinone, MP 158°C to 159°C.
Therapeutic Function
Diuretic
Etozolin Preparation Products And Raw materials
Raw materials
Preparation Products
Etozolin Suppliers
- Tel
- 18871490254
- Fax
- 027-59599243
- linda@hubeijusheng.com
- Country
- CHINA
- ProdList
- 28180
- Advantage
- 58
- Tel
- 15229059051
- 1027@dideu.com
- Country
- China
- ProdList
- 9941
- Advantage
- 58
- Tel
- 18122215013
- 780229652@qq.com
- Country
- China
- ProdList
- 932
- Advantage
- 58
- Tel
- +1-781-999-5354
- support@targetmol.com
- Country
- United States
- ProdList
- 19973
- Advantage
- 58