benzyldimethyl(2-phenoxyethyl)ammonium
- Product Name
- benzyldimethyl(2-phenoxyethyl)ammonium
- CAS No.
- 7181-73-9
- Chemical Name
- benzyldimethyl(2-phenoxyethyl)ammonium
- Synonyms
- benzyldimethyl(2-phenoxyethyl)ammonium;N,N-Dimethyl-N-(2-phenoxyethyl)benzenemethanaminium;Benzenemethanaminium,N,N-dimethyl-N-(2-phenoxyethyl)-
- CBNumber
- CB0879697
- Molecular Formula
- C17H22NO+
- Formula Weight
- 256.36268
- MOL File
- 7181-73-9.mol
benzyldimethyl(2-phenoxyethyl)ammonium Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
Safety
- Hazardous Substances Data
- 7181-73-9(Hazardous Substances Data)
N-Bromosuccinimide Price
- Product number
- CD31000980
- Product name
- Bephenium
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
benzyldimethyl(2-phenoxyethyl)ammonium Chemical Properties,Usage,Production
Originator
Alcopar,Wellcome,UK,1960
Definition
ChEBI: Bephenium is an aromatic amine.
Manufacturing Process
First, dimethylamino-2-phenoxyethanewas made by reacting chloro-2-
phenoxyethane with dimethylamine. Benzyl chloride (10 grams) was then
added to a solution of 1-dimethylamino-2-phenoxyethane (12.3 grams) in
acetone (35 ml). The mixture warmed spontaneously and N-benzyl-N,Ndimethyl-N-2-phenoxyethylammonium chloride slowly crystallized. After 24
hours, this solid was filtered off, washed with fresh acetone and dried
immediately in vacuo, MP 135°-136°C.
2-Hydroxy-3-naphthoic acid (1.88 grams) was dissolved in hot aqueous
sodium hydroxide (0.5N; 20 ml) and the resulting solution was slowly added
to a solution of N-benzyl-N,N-dimethyl-N-2-phenoxyethylammonium chloride
(2.9 grams) in water (5 ml). A gum separated at first but it solidified on
scratching. After the addition was complete, the mixture was allowed to stand
at room temperature for 2 hours and then filtered. The residue was washed
with water and dried in vacuo to give N-benzyl-N,N-dimethyl-N-2-
phenoxyethylammonium 2-hydroxy-3-naphthoate, MP 170°-171°C.
Therapeutic Function
Anthelmintic
benzyldimethyl(2-phenoxyethyl)ammonium Preparation Products And Raw materials
Raw materials
Preparation Products
benzyldimethyl(2-phenoxyethyl)ammonium Suppliers
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