methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride
- Product Name
- methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride
- CAS No.
- 7210-92-6
- Chemical Name
- methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride
- Synonyms
- Baycaine;Tolycaine hydrochloride;LIWOWASNSWUKPF-UHFFFAOYSA-N;methyl 2-[[2-(diethylamino)acetyl]amino]-3-methylbenzoate,hydrochloride;methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride;Benzoic acid,2-[[2-(diethylamino)acetyl]amino]-3-methyl-, methyl ester, hydrochloride (1:1)
- CBNumber
- CB0888921
- Molecular Formula
- C15H23ClN2O3
- Formula Weight
- 314.80772
- MOL File
- 7210-92-6.mol
methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Property
- Melting point:
- 139-140.5°
- storage temp.
- Hygroscopic, Refrigerator, under inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
N-Bromosuccinimide Price
- Product number
- T536625
- Product name
- TolycaineHydrochloride
- Packaging
- 100mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- 467720
- Product name
- Tolycaine Hydrochloride
- Packaging
- 100mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- T536625
- Product name
- TolycaineHydrochloride
- Packaging
- 1g
- Price
- $1455
- Updated
- 2021/12/16
- Product number
- API0004449
- Product name
- TOLYCAINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.3
- Updated
- 2021/12/16
- Product number
- 48990
- Product name
- TolycaineHCl
- Packaging
- 100mg
- Price
- $650
- Updated
- 2021/12/16
methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Chemical Properties,Usage,Production
Originator
Tolycaine Hydrochloride,ZYF Pharm Chemical
Uses
Tolycaine Hydrochloride is an anesthetic drug.
Definition
ChEBI: Tolycaine hydrochloride is an amidobenzoic acid.
Manufacturing Process
A suspension of 40 g 2-amino-3-methylbenzoic acid methyl ester in 125 ml of
benzene was added 125 ml of saturated solution of sodium acetate and then
at 0-5°C was added 37 g chloracetylchloride. The mixture was stirred for 1
hour at room temperature. The mixture was filtered. The organic layer was
with 10% solution of potassium carbonate and dries under calcium chloride.
By distillation of the mixture was obtained 15 g of 2-(2-chloroacetylamino)-3-methylbenzoic acid methyl ester; melting point 86-87.5°C (crystallization from
a mixture acetic acid and ligroin); yield 21.8 g.
A mixture of 16 g of 2-(2-chloroacetylamino)-3-methylbenzoic acid methyl
ester and 10 g diethyl amine in benzene was refluxed for 5 hours. After
cooling the diethyl amine hydrochloride was deleted by filtration. The organic
layer was washed with 2 N hydrochloric acid. To the solution was added
potassium carbonate. The product was extracted with ether and distilled.
Therapeutic Function
Local anesthetic
methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
methyl 2-[[(diethylamino)acetyl]amino]-3-methylbenzoate monohydrochloride Suppliers
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