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amiphenazole

Product Name
amiphenazole
CAS No.
490-55-1
Chemical Name
amiphenazole
Synonyms
Daftazol;Daptazile;Amifenazol;Phenamizol;Phenamizole;Amifenazole;Amiphenazol;amiphenazole;Amifenazol [inn-spanish];2,4-Diamino-5-phenylthiazole
CBNumber
CB0909615
Molecular Formula
C9H9N3S
Formula Weight
191.25
MOL File
490-55-1.mol
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amiphenazole Property

Melting point:
163.5°C (rough estimate)
Boiling point:
413.3±25.0 °C(Predicted)
Density 
1.1906 (rough estimate)
refractive index 
1.5300 (estimate)
pka
5.12±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot
Product number
CD11117196
Product name
5-Phenylthiazole-2,4-diamine
Purity
97%
Packaging
1g
Price
$90
Updated
2021/12/16
Crysdot
Product number
CD11117196
Product name
5-Phenylthiazole-2,4-diamine
Purity
97%
Packaging
5g
Price
$270
Updated
2021/12/16
Crysdot
Product number
CD11117196
Product name
5-Phenylthiazole-2,4-diamine
Purity
97%
Packaging
10g
Price
$450
Updated
2021/12/16
Crysdot
Product number
CD11117196
Product name
5-Phenylthiazole-2,4-diamine
Purity
97%
Packaging
25g
Price
$880
Updated
2021/12/16
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amiphenazole Chemical Properties,Usage,Production

Originator

Aamphisol,RJR

Definition

ChEBI: Amiphenazole is a member of thiazoles.

Manufacturing Process

Thiourea reacted with α-bromophenylacetonitrile and as a result of this reaction 2-(cyanophenylmethyl)isothiourea was obtained.
By cyclisation of the 2-(cyanophenylmethyl)isothiourea 2,4-diamino-5- phenylthiazole (amiphenazol) was produced.

Therapeutic Function

Respiratory stimulant, Barbiturate antagonist, Morphine antagonist

Synthesis Reference(s)

Journal of the American Chemical Society, 73, p. 4517, 1951 DOI: 10.1021/ja01154a005

Purification Methods

The thiazole crystallises from aqueous EtOH or water. Store it in the dark under N2. The hydrochloride has m 273-274o(dec) (from MeOH/EtOAc), and the picrate has m 189-191o(dec) (from H2O). [Davies et al. J Chem Soc 3491 1950, Dodson & Turner J Am Chem Soc 73 4517 1951, Beilstein 27 III/IV 5139.]

amiphenazole Preparation Products And Raw materials

Raw materials

Preparation Products

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amiphenazole Suppliers

Wuhan TCASChem Technology Co., Ltd.
Tel
027-027-86697669 13986148687
Fax
86-027-86697669
Email
sales@tcaschem.com
Country
China
ProdList
3880
Advantage
55
Candia Thamtech Company Limited
Tel
0371-86615086 18203638366 0371-86159066 13526786601
Fax
0371-86159066
Country
China
ProdList
2015
Advantage
60
Tianjing Geneston Bio-tech Co.,Ltd.
Tel
022-60131465 18920720807
Fax
022-58558581
Email
zishan_1986@163.com
Country
China
ProdList
743
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Cato Research Chemicals Inc.
Tel
13342851930
Email
3008394369@qq.com
Country
China
ProdList
15726
Advantage
58

490-55-1, amiphenazoleRelated Search:


  • 5-phenyl-1,3-thiazole-2,4-diamine
  • amiphenazole
  • Amifenazole
  • Daftazol
  • Phenamizol
  • Phenamizole
  • 2,4-Diamino-5-phenylthiazole
  • 2,4-Thiazolediamine, 5-phenyl-
  • 6020-54-8 (Mono-hydrobromide)
  • 942-31-4 (Mono-hydrochloride)
  • Amifenazol
  • Amifenazol [inn-spanish]
  • Amiphenazol
  • 5-phenylthiazole-2,4-diaMine
  • 5-PHENYL-2,4-THIAZOLEDIAMINE
  • Daptazile
  • 490-55-1