amiphenazole

Product Name: amiphenazole
CAS No.: 490-55-1
Chemical Name: amiphenazole
Synonyms: Daftazol;Daptazile;Amifenazol;Phenamizol;Phenamizole;Amifenazole;Amiphenazol;amiphenazole;Amifenazol [inn-spanish];2,4-Diamino-5-phenylthiazole
CBNumber: CB0909615
Molecular Formula: C9H9N3S
Formula Weight: 191.25
MOL File: 490-55-1.mol

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amiphenazole Property

Melting point:: 163.5°C (rough estimate)
Boiling point:: 413.3±25.0 °C(Predicted)
Density: 1.1906 (rough estimate)
refractive index: 1.5300 (estimate)
pka: 5.12±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot

Product number: CD11117196
Product name: 5-Phenylthiazole-2,4-diamine
Purity: 97%
Packaging: 1g
Price: $90
Updated: 2021/12/16

Crysdot

Product number: CD11117196
Product name: 5-Phenylthiazole-2,4-diamine
Purity: 97%
Packaging: 5g
Price: $270
Updated: 2021/12/16

Crysdot

Product number: CD11117196
Product name: 5-Phenylthiazole-2,4-diamine
Purity: 97%
Packaging: 10g
Price: $450
Updated: 2021/12/16

Crysdot

Product number: CD11117196
Product name: 5-Phenylthiazole-2,4-diamine
Purity: 97%
Packaging: 25g
Price: $880
Updated: 2021/12/16

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amiphenazole Chemical Properties,Usage,Production

Originator

Aamphisol,RJR

Definition

ChEBI: Amiphenazole is a member of thiazoles.

Manufacturing Process

Thiourea reacted with α-bromophenylacetonitrile and as a result of this reaction 2-(cyanophenylmethyl)isothiourea was obtained.
By cyclisation of the 2-(cyanophenylmethyl)isothiourea 2,4-diamino-5- phenylthiazole (amiphenazol) was produced.

Therapeutic Function

Respiratory stimulant, Barbiturate antagonist, Morphine antagonist

Synthesis Reference(s)

Journal of the American Chemical Society, 73, p. 4517, 1951 DOI: 10.1021/ja01154a005

Purification Methods

The thiazole crystallises from aqueous EtOH or water. Store it in the dark under N2. The hydrochloride has m 273-274o(dec) (from MeOH/EtOAc), and the picrate has m 189-191o(dec) (from H2O). [Davies et al. J Chem Soc 3491 1950, Dodson & Turner J Am Chem Soc 73 4517 1951, Beilstein 27 III/IV 5139.]

amiphenazole Preparation Products And Raw materials

Raw materials

Preparation Products

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amiphenazole Suppliers

China 6 India 1 Global 7

Wuhan TCASChem Technology Co., Ltd.

Tel: 027-86697669 13986148687
Fax: 86-027-86697669
Email: sales@tcaschem.com
Country: China
ProdList: 4082
Advantage: 55

Candia Thamtech Company Limited

Tel: 0371-86615086 18203638366 0371-86159066 13526786601
Fax: 0371-86159066
Country: China
ProdList: 2017
Advantage: 60

Tianjing Geneston Bio-tech Co.,Ltd.

Tel: 022-60131465 18920720807
Fax: 022-58558581
Email: zishan_1986@163.com
Country: China
ProdList: 742
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28180
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-400-8210725
Email: malulu@leyan.com
Country: China
ProdList: 40041
Advantage: 58

490-55-1, amiphenazoleRelated Search:

Omeprazole 2-AMINO-5-METHYLTHIAZOLE 5-phenylthiazol-2-amine 2,4-DIAMINO-5-PHENYLTHIAZOLE MONOHYDROBROMIDE amiphenazole thiazol-4-amine

5-phenyl-1,3-thiazole-2,4-diamine

amiphenazole

Amifenazole

Daftazol

Phenamizol

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2,4-Diamino-5-phenylthiazole

2,4-Thiazolediamine, 5-phenyl-

6020-54-8 (Mono-hydrobromide)

942-31-4 (Mono-hydrochloride)

Amifenazol

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Amiphenazol

5-phenylthiazole-2,4-diaMine

5-PHENYL-2,4-THIAZOLEDIAMINE

Daptazile

490-55-1