α-Amanitin

Product Name: α-Amanitin
CAS No.: 11030-71-0
Chemical Name: α-Amanitin
Synonyms: α-Amanitin
CBNumber: CB0944238
Molecular Formula: C39H53N9O14S
Formula Weight: 903.95502
MOL File: 11030-71-0.mol

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α-Amanitin Property

Melting point:: 245 °C (decomp)

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Safety

Toxicity: A drug derived from the highly poisonous fungus Amanita phalloides (death cap). Alpha-amanitin, a cyclic octapeptide, is toxic because of its affinity for RNA polymerase II in eukaryotic cells. Since this enzyme is responsible for mRNA synthesis in the cell, the compound is a potent and selective inhibitor of mRNA synthesis. It is effective at concentrations below 1 μg/mL, and its specific action has made it useful in experimental biology. It is often used with actinomycin D to block RNA synthesis.

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Hazard and Precautionary Statements (GHS)

α-Amanitin Preparation Products And Raw materials

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Preparation Products

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11030-71-0, α-AmanitinRelated Search:

α-Amanitin

11030-71-0

C39H54N10O13S