ChemicalBook > CAS DataBase List > 2-(CHLOROMETHYL)-6-METHYLPYRIDINE

2-(CHLOROMETHYL)-6-METHYLPYRIDINE

Product Name
2-(CHLOROMETHYL)-6-METHYLPYRIDINE
CAS No.
3099-29-4
Chemical Name
2-(CHLOROMETHYL)-6-METHYLPYRIDINE
Synonyms
EOS-62430;2-Chloromethyl-6-methylpyridine;2-(Chloromethyl)-6-methylpyridin;Pyridine, 2-(chloromethyl)-6-methyl-;2-(chloromethyl)-6-methylpyridine(SALTDATA: HCl);2-(CHLOROMETHYL)-6-METHYLPYRIDINE ISO 9001:2015 REACH
CBNumber
CB0955607
Molecular Formula
C7H8ClN
Formula Weight
141.6
MOL File
3099-29-4.mol
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2-(CHLOROMETHYL)-6-METHYLPYRIDINE Property

Melting point:
159-161 °C
Boiling point:
118-120 °C(Press: 65 Torr)
Density 
1.118±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
4.43±0.12(Predicted)
Appearance
Light brown to brown Liquid
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CBR01903
Product name
2-(Chloromethyl)-6-methylpyridine
Purity
Aldrich<SUP>CPR</SUP>
Packaging
1 g
Price
$179
Updated
2025/07/31
TRC
Product number
C381723
Product name
2-(Chloromethyl)-6-methylpyridine
Packaging
1g
Price
$330
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC148709
Product name
2-(Chloromethyl)-6-methylpyridine
Packaging
250mg
Price
$367.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC148709
Product name
2-(Chloromethyl)-6-methylpyridine
Packaging
100mg
Price
$184
Updated
2021/12/16
Apolloscientific
Product number
OR450025
Product name
2-(Chloromethyl)-6-methylpyridine
Packaging
1g
Price
$53
Updated
2021/12/16
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2-(CHLOROMETHYL)-6-METHYLPYRIDINE Chemical Properties,Usage,Production

Synthesis

1122-71-0

3099-29-4

Preparation of Example 10-1-1 2-chloromethyl-6-methylpyridine: (6-methylpyridin-2-yl)methanol (1.44 g, 11.7 mmol) was dissolved in dichloromethane (20 mL) and thionyl chloride (1.45 mL, 19.9 mmol) was added. The reaction mixture was stirred under reflux conditions for 40 min. Upon completion of the reaction, the reaction solution was cooled to room temperature and subsequently concentrated under reduced pressure. The concentrated residue was partitioned between sodium bicarbonate solution and ether. The organic layer was separated and concentrated under reduced pressure, and the resulting residue was purified by silica gel column chromatography (eluent: ethyl acetate) to afford the target product 2-chloromethyl-6-methylpyridine (1.42 g, 85.8% yield).1H-NMR (DMSO-d6) δ (ppm): 2.47 (3H, s), 4.72 (2H, s), 7.22 (1H, d, J = 7.6 Hz), 7.33 (1H, d, J = 7.6 Hz), 7.72 (1H, dd, J = 7.6, 7.6 Hz).

References

[1] Journal of the American Chemical Society, 2005, vol. 127, # 29, p. 10197 - 10204
[2] Patent: US2009/82403, 2009, A1. Location in patent: Page/Page column 64
[3] Patent: US2007/105904, 2007, A1. Location in patent: Page/Page column 61
[4] Chinese Chemical Letters, 2018, vol. 29, # 11, p. 1637 - 1640
[5] Chemistry Letters, 1998, # 9, p. 915 - 916

2-(CHLOROMETHYL)-6-METHYLPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(CHLOROMETHYL)-6-METHYLPYRIDINE Suppliers

J & K SCIENTIFIC LTD.
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JinYan Chemicals(ShangHai) Co.,Ltd.
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Shanghai Topbiochem Technology Co., Ltd
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View Lastest Price from 2-(CHLOROMETHYL)-6-METHYLPYRIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-(CHLOROMETHYL)-6-METHYLPYRIDINE 3099-29-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-10
Dideu Industries Group Limited
Product
2-(CHLOROMETHYL)-6-METHYLPYRIDINE 3099-29-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-30
Career Henan Chemical Co
Product
2-(CHLOROMETHYL)-6-METHYLPYRIDINE 3099-29-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-09