ChemicalBook > CAS DataBase List > 4-(4-Chlorophenyl)butanoic acid

4-(4-Chlorophenyl)butanoic acid

Product Name
4-(4-Chlorophenyl)butanoic acid
CAS No.
4619-18-5
Chemical Name
4-(4-Chlorophenyl)butanoic acid
Synonyms
4-Chlorobenzenebutanoic acid;-(4-Chlorophenyl)butanic acid;4-(4-Chlorophenyl)butanic acid;Benzenebutanoic acid, 4-chloro-;4-(4-chlorophenyl)butanoic acid;4-(4-CHLORO-PHENYL)-BUTYRIC ACID;4-(4-chlorophenyl)butanoic acid(SALTDATA: FREE)
CBNumber
CB0958426
Molecular Formula
C10H11ClO2
Formula Weight
198.65
MOL File
4619-18-5.mol
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4-(4-Chlorophenyl)butanoic acid Property

Melting point:
55 °C
Boiling point:
181-184 °C
Density 
1.227±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
4.74±0.10(Predicted)
Appearance
White to light brown Solid
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Safety

HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C994588
Product name
4-(4-Chlorophenyl)butyricAcid
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
J50680
Product name
4-(4-Chlorophenyl)butyricacid
Packaging
25g
Price
$280
Updated
2021/12/16
Rieke Metals
Product number
C0102
Product name
4-(4-Chlorophenyl)butyricacid
Packaging
1g
Price
$661
Updated
2021/12/16
Matrix Scientific
Product number
177177
Product name
4-(4-Chlorophenyl)butanoic acid
Packaging
1g
Price
$720
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0055362
Product name
4-(4-CHLOROPHENYL)BUTANOIC ACID
Purity
95.00%
Packaging
1G
Price
$867.1
Updated
2021/12/16
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4-(4-Chlorophenyl)butanoic acid Chemical Properties,Usage,Production

Synthesis

3984-34-7

4619-18-5

General procedure for the synthesis of 4-(4-chlorophenyl)butyric acid from 3-(4-chlorobenzoyl)propionic acid: A mixture of 4-(4-chlorophenyl)-4-oxobutanoic acid (1 eq.), potassium hydroxide (KOH, 3 eq.), and hydrazine hydrate (2.2 eq.) in ethylene glycol was placed in a reaction flask and azeotropically refluxed for 5 hr at 120-130 °C. Subsequently, the reaction temperature was gradually increased to 180 °C and the reflux was continued at 190 °C for 3 hours. After completion of the reaction, the reaction mixture was cooled to 25 °C, diluted with water and poured into 2.5 N hydrochloric acid (HCl) solution for acidification, and white crystals were precipitated to give 4-(4-chlorophenyl)butyric acid in 89% yield.

References

[1] Patent: US6410585, 2002, B1
[2] Journal of Medicinal Chemistry, 1982, vol. 25, # 8, p. 947 - 952
[3] Patent: US2005/165004, 2005, A1. Location in patent: Page/Page column 28
[4] Patent: WO2015/134973, 2015, A1. Location in patent: Page/Page column 97; 98
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 41, p. 12476 - 12480

4-(4-Chlorophenyl)butanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-(4-Chlorophenyl)butanoic acid manufacturers

Shanghai UCHEM Inc.
Product
4-(4-Chlorophenyl)butanoic acid 4619-18-5
Price
US $15.00-125.00/g
Min. Order
5g
Purity
0.98
Supply Ability
25kg
Release date
2023-12-08
Honest Joy Holdings Limited
Product
4-(4-Chlorophenyl)butanicacid 4619-18-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98.4%
Supply Ability
100 tons
Release date
2022-01-14
Career Henan Chemical Co
Product
4-(4-Chlorophenyl)butanic acid 4619-18-5
Price
US $10.00-2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100
Release date
2018-07-23

4619-18-5, 4-(4-Chlorophenyl)butanoic acidRelated Search:

3-(4-Chlorobenzoyl)propionic acid 3-(P-CHLOROBENZOYL)-BUTYRIC ACID 4-(4-CHLOROPHENYL)-2-(4-METHYLPHENYL)-4-OXOBUTANOIC ACID ETHYL 2-ACETYL-4-(4-CHLOROPHENYL)-4-OXOBUTANOATE 3-BROMO-4-(4-CHLORO-PHENYL)-4-OXO-BUTYRIC ACID METHYL 4-(4-CHLOROPHENYL)-2-(4-METHYLPHENYL)-4-OXOBUTANOATE 4-(2,4-DICHLOROPHENYL)-4-OXOBUTYRIC ACID 2-(3-chlorophenyl)-4-(4-chlorophenyl)-4-oxobutanoic acid 4-(4-CHLORO-PHENYL)-4-OXO-BUTYRIC ACID ETHYL ESTER 4-(4-CHLOROPHENYL)-2-(2,3-DICHLOROPHENYL)-4-OXOBUTANOIC ACID METHYL 4-(4-CHLOROPHENYL)-2-(2,4-DICHLOROPHENYL)-4-OXOBUTANOATE 4-(4-CHLOROPHENYL)-2-(3-METHYL-5-OXO-1-PHENYL(2-PYRAZOLIN-4-YL))-4-OXOBUTANOIC ACID 4-(4-CHLOROPHENYL)-2-(2,4-DICHLOROPHENYL)-4-OXOBUTANOIC ACID CLIDANAC METHYL 4-(4-CHLOROPHENYL)-2-(2,3-DICHLOROPHENYL)-4-OXOBUTANOATE 4-(4-CHLOROPHENYL)-2,4-DIOXOBUTANOIC ACID METHYL 2-(3-CHLOROPHENYL)-4-(4-CHLOROPHENYL)-4-OXOBUTANOATE METHYL 4-(4-CHLOROPHENYL)-2-(4-ETHYLPHENYL)-4-OXOBUTANOATE

  • 4-(4-Chlorophenyl)butanic acid
  • 4-(4-chlorophenyl)butanoic acid(SALTDATA: FREE)
  • Benzenebutanoic acid, 4-chloro-
  • 4-Chlorobenzenebutanoic acid
  • -(4-Chlorophenyl)butanic acid
  • 4-(4-CHLORO-PHENYL)-BUTYRIC ACID
  • 4-(4-chlorophenyl)butanoic acid
  • 4619-18-5