ER-Tracker Green
- Product Name
- ER-Tracker Green
- CAS No.
- 730931-46-1
- Chemical Name
- ER-Tracker Green
- Synonyms
- ER-Tracker Green;5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-3-(3-(5,5-difluoro-7,9-dimethyl-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)propanamido)-2-methoxybenzamide;5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-3-(3-(5,5-difluoro-7,9-dimethyl-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)propanamido)-2-methoxybenzamide;Boron, [N-[5-chloro-3-[[[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]amino]carbonyl]-2-methoxyphenyl]-5-[(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrole-2-propanamidato-κN1]difluoro-, (T-4)-
- CBNumber
- CB09618891
- Molecular Formula
- C37H42BClF2N6O6S
- Formula Weight
- 783.09
- MOL File
- 730931-46-1.mol
ER-Tracker Green Property
- form
- Solid
- color
- Brown to reddish brown
ER-Tracker Green Chemical Properties,Usage,Production
Uses
ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation[1].
References
[1] Tanuja T Merianda, et al. A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci. 2009 Feb;40(2):128-42. DOI:10.1016/j.mcn.2008.09.008
[2] Merianda TT, et al. A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci. 2009 Feb;40(2):128-42.
[3] J Jacob Strouse, et al. Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters. Anal Biochem. 2013 Jun 1;437(1):77-87. DOI:10.1016/j.ab.2013.02.018
ER-Tracker Green Preparation Products And Raw materials
Raw materials
Preparation Products
ER-Tracker Green Suppliers
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- 021-68781987 13818305065
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View Lastest Price from ER-Tracker Green manufacturers
- Product
- ER-Tracker Green 730931-46-1
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- >98.00%
- Supply Ability
- 5mg
- Release date
- 2024-03-29